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Vitronectin antibody | BV2

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Mouse anti Human Vitronectin

Product Type
Monoclonal Antibody
Clone
BV2
Isotype
IgG1
Product Code Applications Pack Size List Price Quantity
OBT1722
Datasheet
C E F IP WB
MSDS
0.1 mg loader

Mouse anti Human vitronectin antibody, clone BV2 recognizes human vitronectin, also known as S-protein, serum spreading factor or V75. Vitronectin is a 459 amino acid ~55 kDa cell adhesion and spreading factor found in serum and tissue.

Product Details

Target Species
Human
Product Form
Purified IgG - liquid
Preparation
Purified IgG prepared by affinity chromatography on Protein A
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.05% Sodium Azide (NaN3)
Immunogen
Purified human plasma vitronectin.
Approx. Protein Concentrations
IgG concentration 0.1 mg/ml

Storage Information

Storage
Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Guarantee
12 months from date of despatch

More Information

UniProt
P04004
Entrez Gene
VTN
GO Terms
GO:0005044 scavenger receptor activity
GO:0005178 integrin binding
GO:0005615 extracellular space
GO:0006955 immune response
GO:0008201 heparin binding
GO:0010951 negative regulation of endopeptidase activity
GO:0014911 positive regulation of smooth muscle cell migration
GO:0030195 negative regulation of blood coagulation
GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway
GO:0032092 positive regulation of protein binding
GO:0033627 cell adhesion mediated by integrin
GO:0048260 positive regulation of receptor-mediated endocytosis
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
GO:0061302 smooth muscle cell-matrix adhesion
GO:0071062 alphav-beta3 integrin-vitronectin complex
GO:0090303 positive regulation of wound healing
Regulatory
For research purposes only

Applications of Vitronectin antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
ELISA
Flow Cytometry
Immunohistology - Frozen
Immunoprecipitation
Western Blotting
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Copyright © 2020 Bio-Rad Antibodies (formerly AbD Serotec)

Secondary Antibodies Available

Description Product Code Applications Pack Size List Price Quantity
Goat anti Mouse IgG (H/L):Alk. Phos. (Multi Species Adsorbed) STAR117A E WB 0.5 mg loader
Goat anti Mouse IgG (H/L):DyLight®488 (Multi Species Adsorbed) STAR117D488GA F IF 0.1 mg loader
Goat anti Mouse IgG (H/L):DyLight®680 (Multi Species Adsorbed) STAR117D680GA F WB 0.1 mg loader
Goat anti Mouse IgG (H/L):DyLight®800 (Multi Species Adsorbed) STAR117D800GA F IF WB 0.1 mg loader
Goat anti Mouse IgG (H/L):FITC (Multi Species Adsorbed) STAR117F F 0.5 mg loader
Goat anti Mouse IgG (H/L):HRP (Multi Species Adsorbed) STAR117P E WB 0.5 mg loader
Goat anti Mouse IgG (Fc):FITC STAR120F C F 1 mg loader
Goat anti Mouse IgG (Fc):HRP STAR120P E WB 1 mg loader
Rabbit F(ab')2 anti Mouse IgG:RPE STAR12A F 1 ml loader
Rabbit F(ab')2 anti Mouse IgG:HRP (Human Adsorbed) STAR13B C E P RE WB 1 mg loader
Goat anti Mouse IgG:FITC (Rat Adsorbed) STAR70 F 0.5 mg loader
Goat anti Mouse IgG:RPE (Rat Adsorbed) STAR76 F 1 ml loader
Goat anti Mouse IgG:HRP (Rat Adsorbed) STAR77 C E P 0.5 mg loader
Goat anti Mouse IgG/A/M:Alk. Phos. STAR87A C E WB 1 mg loader
Goat anti Mouse IgG/A/M:HRP (Human Adsorbed) STAR87P E 1 mg loader
Rabbit F(ab')2 anti Mouse IgG:Dylight®800 STAR8D800GA F IF WB 0.1 mg loader
Rabbit F(ab')2 anti Mouse IgG:FITC STAR9B F 1 mg loader

Negative Isotype Controls Available

Description Product Code Applications Pack Size List Price Quantity
Mouse IgG1 Negative Control MCA928 F 100 Tests loader

Product Specific References

Source Reference

  1. Zanetti, A. et al. (1994) Clustering of vitronectin and RGD peptides on microspheres leads to engagement of integrins on the luminal aspect of endothelial cell membrane.
    Blood. 84 (4): 1116-23.
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