VISA antibody | OTI8A11

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Anti VISA Antibody, clone OTI8A11 (PrecisionAb Monoclonal Antibody) thumbnail image 1

Anti VISA Antibody, clone OTI8A11 (PrecisionAb Monoclonal Antibody) gallery image 1 — Western blot analysis of whole cell lysates probed with VISA antibody followed by detection with HRP conjugated Goat anti Mouse IgG (1/10,000, STAR207P) and visualized on the ChemiDoc MP with 46 second exposure. Arrow points to VISA (molecular weight 75 kDa).

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Mouse anti VISA

Product Type: PrecisionAb Monoclonal
Clone: OTI8A11
Isotype: IgG1
Format: Purified
Specificity: VISA

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Mouse anti Human VISA antibody, clone OTI8A11 recognizes virus-induced signaling adaptor (VISA), also known as MAVS, CARD adapter inducing interferon beta, interferon beta promoter stimulator protein 1, mitochondrial antiviral-signaling protein and putative NF-kappa-B-activating protein 031N.

Encoded by the MAVS gene, VISA is an intermediary protein necessary in the virus-triggered beta interferon signaling pathways. It is required for activation of transcription factors which regulate expression of beta interferon and contributes to antiviral immunity. Multiple transcript variants encoding different isoforms have been found for MAVS or VISA (provided by RefSeq, Sep 2011).

Mouse anti Human VISA antibody, clone OTI8A11 detects a band of 75 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.

Target Species: Human
Western Blotting: Anti VISA detects a band of approximately 75 kDa in A431 cell lysates.
Product Form: Purified IgG - liquid
Preparation: Mouse monoclonal antibody purified by affinity chromatography from ascites.
Buffer Solution: Phosphate buffered saline.
Preservative Stabilisers: 0.09% Sodium Azide (NaN₃)
1% Bovine Serum Albumin
50% Glycerol
Immunogen: Recombinant protein fragment corresponding to aa 1-247 of human VISA (NP_065797) produced in E.coli
Regulatory: For research purposes only.
Guarantee: 12 months from date of despatch.
Acknowledgements: PrecisionAb is a trademark of Bio-Rad Laboratories.

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

Application Name	Verified	Min Dilution	Max Dilution
Western Blotting		1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.