Unconventional Myosin 6 antibody | CD02/3A9
Filter by Application:
WB ResetMouse anti Unconventional Myosin 6
- Product Type
- PrecisionAb Monoclonal
- Clone
- CD02/3A9
- Isotype
- IgG1
- Format
- Purified
- Specificity
- Unconventional Myosin 6
Quick Links:
Antibody Quality and 
Unrivaled 
| Mouse anti Unconventional Myosin 6 antibody recognizes unconventional myosin-6 (MYO6). Unconventional Myosin 6 is an actin-based motor protein which moves cargo towards the minus end of actin filaments, in the opposite direction to every other myosin. Due to its unique function, and its role in a wide variety of cellular processes including endocytosis, polarized secretion, and autophagy (Masters et al. 2017). Unconventional Myosin 6 upregulation is a hallmark of various cancer types, is critical for maintaining malignant properties, and contributes to tumor cell migration and metastasis (Lei et al. 2017). The loss or overexpression of Unconventional Myosin 6 is also associated with neurodegenerative diseases, cardiomyopathy, deafness, and other pathologies (de Jonge et al. 2019). |
|
- Target Species
- Human
- Western Blotting
- Mouse anti unconventional myosin 6 antibody detects a band of approximately 140 kDa in MCF-7 cell lysates
- Product Form
- Purified IgG - Liquid
- Preparation
- Mouse monoclonal antibody affinity purified on Protein G from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide
- Immunogen
- E. coli-derived recombinant protein of amino acids 1042-1294 of human MYO6
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Fusion Partners
- Spleen cells from immunised BALB/c mice were fused with cells of the mouse SP2/0 myeloma cell line
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories
Store undiluted at -20°C, avoiding repeated freeze thaw cycles
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting |  |
1/500 | 1/2000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
|---|---|---|---|---|---|---|---|
| Goat anti Mouse IgG (H/L):HRP | STAR207P | WB | 2 ml |
 |
Log in | ||
| List Price | Your Price | ||||||
|
|
Log in | ||||||
| Description | Goat anti Mouse IgG (H/L):HRP | ||||||
- UniProt
- Q9UM54
- Entrez Gene
- MYO6
- GO Terms
- GO:0005515 protein binding
- GO:0051015 actin filament binding
- GO:0005829 cytosol
- GO:0005516 calmodulin binding
- GO:0005524 ATP binding
- GO:0005794 Golgi apparatus
- GO:0005905 coated pit
- GO:0005938 cell cortex
- GO:0006897 endocytosis
- View More GO Terms
- GO:0007268 synaptic transmission
- GO:0007605 sensory perception of sound
- GO:0030048 actin filament-based movement
- GO:0016461 unconventional myosin complex
- GO:0016591 DNA-directed RNA polymerase II, holoenzyme
- GO:0030330 DNA damage response, signal transduction by p53 class mediator
- GO:0030665 clathrin coated vesicle membrane
- GO:0031941 filamentous actin
- GO:0031965 nuclear membrane
- GO:0032587 ruffle membrane
- GO:0043531 ADP binding
- GO:0045944 positive regulation of transcription from RNA polymerase II promoter
- GO:0048471 perinuclear region of cytoplasm
- GO:0051046 regulation of secretion
- GO:0060001 minus-end directed microfilament motor activity
Request a different product with this specificity
Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
View all Anti-Human ProductsAlways be the first to know.
When we launch new products and resources to help you achieve more in the lab.
Yes, sign me up