TSLP antibody | D01-2E2
Mouse anti Human TSLP:Biotin
- Product Type
- Monoclonal Antibody
- Clone
- D01-2E2
- Isotype
- IgG1
- Specificity
- TSLP
Antibody Quality and Performance Guarantee
| Mouse anti Human TSLP antibody, clone D01-2E2, recognizes thymic stromal lymphopoietin (TSLP), a member of the interleukin-2 (IL-2) cytokine family and an IL-7-like cytokine. TSLP plays a role in pathophysiological immunity-related functions. Specifically, TSLP is implicated in allergic reaction, infection, cancer and autoimmunity (Ziegler et al. 2013). During allergic inflammation, the primary producers of TSLP are epithelial cells, keratinocytes, mast cells, smooth muscle cells, dendritic cells and trophoblasts (Takai 2012). TSLP is a ligand of the TSLP receptor (TSLPR), which is expressed by a variety of hematopoietic cell populations and some hematopoietic cells such as epithelial cells (Ziegler et al. 2013).Upon binding of TSLP to TSLPR various signaling pathways can be activated including JAK, STAT, Src kinases and PI3K. Under physiological conditions, induction of these pathways can promote homeostatic polyclonal expansion of T cells in the absence of foreign antigens and drive differentiation of inducible Tregs (Nakajima et al. 2020). The biotinylated Mouse anti Human TSLP antibody, clone D01-2E2 (MCA6285B) can be used as a detection antibody in a sandwich ELISA with the purified Mouse anti Human TSLP antibody, clone H03-5E12 (MCA6284GA) as the capture antibody. |
- Target Species
- Human
- Product Form
- Purified IgG conjugated to Biotin - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
1% Bovine Serum Albumin - Immunogen
- E. Coli derived recombinant full length human TSLP (Tyr29-Gln159)
- Approx. Protein Concentrations
- IgG concentration 0.1 mg/ml
- Fusion Partners
- Cell fusion between immunized BALB/c mouse spleen cells and mouse myeloma SP2/0
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| ELISA |  |
1.0 ug/ml |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
How to Use the Spectraviewer
Watch the Tool Tutorial Video ▸- Start by selecting the application you are interested in, with the option to select an instrument from the drop down menu or create a customized instrument
- Select the fluorophores or fluorescent proteins you want to include in your panel to check compatibility
- Select the lasers and filters you wish to include
- Select combined or multi-laser view to visualize the spectra
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
|---|---|---|---|---|---|---|---|
| Mouse anti Human TSLP | MCA6284GA | E | 0.1 mg |
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| Description | Mouse anti Human TSLP | ||||||
- UniProt
- Q969D9
- Entrez Gene
- TSLP
- GO Terms
- GO:0005125 cytokine activity
- GO:0005615 extracellular space
MCA6285B
100005190
If you cannot find the batch/lot you are looking for please contact our technical support team for assistance.
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