TSC1 antibody | OTI3A2

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Anti TSC1 Antibody, clone OTI3A2 (PrecisionAb Monoclonal Antibody) thumbnail image 1

Anti TSC1 Antibody, clone OTI3A2 (PrecisionAb Monoclonal Antibody) gallery image 1 — Western blot analysis of whole cell lysates probed with TSC1 antibody (**VMA00181**) followed by detection with HRP conjugated Goat anti Mouse IgG (1/10,000, STAR207P) and visualized on the ChemiDoc MP with 105 second exposure. Arrow points to TSC1 (molecular weight 150 kDa).

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Mouse anti TSC1

Product Type: PrecisionAb Monoclonal
Clone: OTI3A2
Isotype: IgG2a
Format: Purified
Specificity: TSC1

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Product Code Applications Pack Size List Price Your Price Qty

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VMA00181 Datasheet Datasheet SDS SDS	WB	100 µl		Log in	Get Quote
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Mouse anti Human TSC1 antibody recognizes TSC1, also known as hamartin and tuberous sclerosis 1 protein.

TSC1 encodes a growth inhibitory protein thought to play a role in the stabilization of tuberin. Mutations in TSC1 have been associated with tuberous sclerosis. Alternative splicing results in multiple transcript variants (provided by RefSeq, Jun 2009).

Mouse anti Human TSC1 antibody detects a band of 150 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.

Target Species: Human
Western Blotting: Anti TSC1 detects a band of approximately 150 kDa in Jurkat cell lysates.
Product Form: Purified IgG - liquid
Preparation: Mouse monoclonal antibody purified by affinity chromatography from ascites.
Buffer Solution: Phosphate buffered saline.
Preservative Stabilisers: 0.09% Sodium Azide (NaN₃)
1% Bovine Serum Albumin
50% Glycerol
Immunogen: Human recombinant protein fragment corresponding to amino acids 836-1164 of human TSC1 (NP_000359) produced in E. coli
Regulatory: For research purposes only.
Guarantee: 12 months from date of despatch.
Acknowledgements: PrecisionAb is a trademark of Bio-Rad Laboratories.

Store undiluted at -20° C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

Application Name	Verified	Min Dilution	Max Dilution
Western Blotting		1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Description	Product Code	Applications	Pack Size	Your Price
Goat anti Mouse IgG (H/L):HRP	STAR207P	WB	2 ml	Log in	Get Quote
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Description	Goat anti Mouse IgG (H/L):HRP

UniProt: Q92574
Entrez Gene: TSC1
GO Terms: GO:0051087 chaperone binding; GO:0016020 membrane; GO:0005938 cell cortex; GO:0006407 rRNA export from nucleus; GO:0007050 cell cycle arrest; GO:0007160 cell-matrix adhesion; GO:0008285 negative regulation of cell proliferation; GO:0008286 insulin receptor signaling pathway; GO:0017148 negative regulation of translation; View More GO Terms; GO:0030027 lamellipodium; GO:0031397 negative regulation of protein ubiquitination; GO:0032007 negative regulation of TOR signaling cascade; GO:0032862 activation of Rho GTPase activity; GO:0033596 TSC1-TSC2 complex; GO:0043666 regulation of phosphoprotein phosphatase activity; GO:0047485 protein N-terminus binding; GO:0051492 regulation of stress fiber assembly; GO:0051894 positive regulation of focal adhesion assembly