Thyroglobulin antibody | 5E6 (BGN/6D7)
PHP236
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E ResetMouse anti Human Thyroglobulin
- Product Type
- Monoclonal Antibody
- Clone
- 5E6 (BGN/6D7)
- Isotype
- IgG2b
- Specificity
- Thyroglobulin
Antibody Quality and 
Unrivaled 
| Mouse anti Human Thyroglobulin antibody, clone 5E6 recognizes human thyroglobulin (Tg), a 2768 amino acid ~670kDa homodimeric protein containing multiple thyroglobulin type 1 domains. Thyroglobulin is produced by the thyroid gland and is a precursor in the production of the thyroid hormones Triiodothyronine (T3) and Thyroxine (T4), important for regulating metabolic processes in the body (UniProt: P01266). Mutations in the thyroglobulin gene can lead to developmental and autoimmune diseases including Thyroid dyshormonogenesis 3 (Targovnik et al. 2010) and Autoimmune thyroid disease 3 (Ban et al. 2003). Mouse anti Human Thyroglobulin antibody, clone 5E6 has been used successfully as a detection reagent in a sensitive sandwich ELISA for the detection of thyroglobulin in human serum and plasma samples. |
- Target Species
- Human
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- <0.1% Sodium Azide (NaN3)
- Immunogen
- Purified human thyroglobulin.
- Approx. Protein Concentrations
- 1.0 mg/ml
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| ELISA |  |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.
- ELISA
- 8900-0730 is suitable for use as a detection antibody in a sandwich ELISA using 8900-0700 as the capture antibody.
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
|---|---|---|---|---|---|---|---|
| Mouse anti Human Thyroglobulin | 8900-0700 | E | 1 mg |
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| Description | Mouse anti Human Thyroglobulin | ||||||
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