Mouse anti superoxidase dismutase (Mn), clone 2A1, recognizes superoxide dismutase 2 (Mn) also known as superoxide dismutase 2 (SOD2). SOD2 is an anti oxidant enzyme involved in the body's defense against reactive oxygen species. Superoxide dismutases destroy damaging free radicals that are produced within cells and are toxic to biological systems.
- Target Species
- Species Cross-Reactivity
|Target Species||Cross Reactivity|
- N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Purified IgG prepared by affinity chromatography on Protein G
- Buffer Solution
- HEPES buffered saline
- Preservative Stabilisers
- 0.03% Sodium Azide (NaN3)
0.01% Bovine Serum Albumin
- Recombinant human protein purified from E.coli
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Store at -20oC only.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
- 12 months from date of despatch
- Entrez Gene
- GO Terms
age-dependent response to reactive oxygen species
release of cytochrome c from mitochondria
vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure
superoxide dismutase activity
regulation of transcription from RNA polymerase II promoter
removal of superoxide radicals
manganese ion binding
negative regulation of neuron apoptosis
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of Superoxide Dismutase (MN) antibody
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- Western Blotting
- Mouse anti superoxide dismutase (Mn) recognizes a band of approximately 23 kDa in HeLa and HepG2 cell lysates and mouse and rat brain tissue lysates
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Secondary Antibodies Available