STAT6 antibody | 6C10
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IF P WB ResetMouse anti Human STAT6:Preservative Free
- Product Type
- Monoclonal Antibody
- Clone
- 6C10
- Isotype
- IgG2b
- Specificity
- STAT6
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| Mouse anti Human STAT6 antibody, clone 6C10 recognizes human Signal transducer and activator of transcription 6, also known as STAT6 or IL-4 Stat. STAT6 is a 846 amino acid ~100 kDa tignal transducer and activator of transcription involved in interleukin-4 and interleukin-3 signaling. Changes in STAT6 expression has been implicated in the development of Hemangiopericytoma and solitary fibrous tumor (Doyle et al. 2014).Mouse anti Human STAT6 antibody, clone 6C10 recognizes human Signal transducer and activator of transcription 6, also known as STAT6 or IL-4 Stat. STAT6 is a 846 amino acid ~100 kDa signal transducer and activator of transcription involved in interleukin-4 and interleukin-3 signaling. Changes in STAT6 expression has been implicated in the development of Hemangiopericytoma and solitary fibrous tumor (Doyle et al. 2014). |
- Target Species
- Human
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein A
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- None present
- Immunogen
- Recombinant protein corresponding to aa 695-804 of human STAT6
- Approx. Protein Concentrations
- IgG concentration 0.5 mg/ml
- Fusion Partners
- Spleen cells from immunized Balb/c mice were fused with cells from the Sp2/0 myeloma cell line.
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
Store at -20oC only.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Immunofluorescence |  |
0.1 | 10 ug/ml |
| Immunohistology - Paraffin 1 | |
0.1 | 10 ug/ml |
| Western Blotting | |
- 1This product requires antigen retrieval using heat treatment prior to staining of paraffin sections.Sodium citrate buffer pH 6.0 is recommended for this purpose.
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- RRID
- AB_2197250
- UniProt
- P42226
- Entrez Gene
- STAT6
- GO Terms
- GO:0005515 protein binding
- GO:0005509 calcium ion binding
- GO:0003700 sequence-specific DNA binding transcription factor activity
- GO:0005829 cytosol
- GO:0004871 signal transducer activity
- GO:0005634 nucleus
View more products with STAT6 specificity
Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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