STAT6 antibody | 6C10

Mouse anti Human STAT6:Preservative Free

Product Type
Monoclonal Antibody
Clone
6C10
Isotype
IgG2b
Specificity
STAT6

Product Code Applications Pack Size List Price Your Price Qty
MCA3474Z
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
IF P * WB 100 µg loader
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loader
Search for Batch Specific Datasheets

Mouse anti Human STAT6 antibody, clone 6C10 recognizes human Signal transducer and activator of transcription 6, also known as STAT6 or IL-4 Stat. STAT6 is a 846 amino acid ~100 kDa tignal transducer and activator of transcription involved in interleukin-4 and interleukin-3 signaling.

Changes in STAT6 expression has been implicated in the development of Hemangiopericytoma and solitary fibrous tumor (Doyle et al. 2014).Mouse anti Human STAT6 antibody, clone 6C10 recognizes human Signal transducer and activator of transcription 6, also known as STAT6 or IL-4 Stat. STAT6 is a 846 amino acid ~100 kDa signal transducer and activator of transcription involved in interleukin-4 and interleukin-3 signaling.

Changes in STAT6 expression has been implicated in the development of Hemangiopericytoma and solitary fibrous tumor (Doyle et al. 2014).

Target Species
Human
Product Form
Purified IgG - liquid
Preparation
Purified IgG prepared by affinity chromatography on Protein A from ascites
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
None present
Immunogen
Recombinant protein corresponding to aa 695-804 of human STAT6
Approx. Protein Concentrations
IgG concentration 0.5 mg/ml
Fusion Partners
Spleen cells from immunized Balb/c mice were fused with cells from the Sp2/0 myeloma cell line.
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

Store at -20oC only.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Immunofluorescence 0.1 10 ug/ml
Immunohistology - Paraffin 1 0.1 10 ug/ml
Western Blotting
  1. 1This product requires antigen retrieval using heat treatment prior to staining of paraffin sections.Sodium citrate buffer pH 6.0 is recommended for this purpose.
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

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RRID
AB_2197250
UniProt
P42226
Entrez Gene
STAT6
GO Terms
GO:0005515 protein binding
GO:0005509 calcium ion binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005829 cytosol
GO:0004871 signal transducer activity
GO:0005634 nucleus
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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