SATB2 antibody | RM365

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Rabbit anti SATB2

Product Type
Monoclonal Antibody
Clone
RM365
Isotype
IgG
Product Code Applications Pack Size List Price Quantity
MCA6351
Datasheet
P WB
SDS
0.1 ml loader

Rabbit anti SATB2 antibody recognizes DNA-binding protein SATB2, also known as special AT-rich sequence-binding protein 2.

SATB2 is a transcription factor which can bind to matrix-attachment regions (MARs) and activate transcription of multiple genes simultaneously. This allows SATB2 to act as a high-level regulator of multiple networks involved with development (Zarate and Fish 2016). SATB2 is highly expressed in the brain and plays a role in development of the central nervous system and neocortical organization. It also plays a role in differentiation of osteoblasts (Berg et al. 2016). Mutations in the gene encoding SATB2 can lead to SATB2-associated syndrome, characterized by developmental delay, intellectual disability, speech and behavioural problems, and craniofacial abnormalities (Whitton et al. 2018).

Product Details

Target Species
Human
Product Form
Purified IgG - liquid
Preparation
Purified IgG prepared by affinity chromatography on Protein A from animal origin-free culture supernatant
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide
1% Bovine Serum Albumin
50% Glycerol
Immunogen
A peptide corresponding to the C-terminus of human DNA-binding protein SATB2

Storage Information

Storage
Store at -20°C only.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.
Guarantee
12 months from date of despatch

More Information

UniProt
Q9UPW6
Entrez Gene
SATB2
GO Terms
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005737 cytoplasm
GO:0016363 nuclear matrix
Regulatory
For research purposes only

Applications of SATB2 antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Immunohistology - Paraffin 1/200 1/1000
Western Blotting 1/1000 1/2000
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

Secondary Antibodies Available

Description Product Code Applications Pack Size List Price Quantity
Goat anti Rabbit IgG (Fc):Biotin STAR121B E WB 1 mg loader
Goat anti Rabbit IgG (Fc):FITC STAR121F F 1 mg loader
Goat anti Rabbit IgG (Fc):HRP STAR121P E WB 1 mg loader
Goat anti Rabbit IgG (H/L):HRP STAR124P C E WB 1 mg loader
Sheep anti Rabbit IgG:FITC STAR34B C F 1 mg loader
Sheep anti Rabbit IgG:RPE STAR35A F 1 ml loader
Sheep anti Rabbit IgG:DyLight®488 STAR36D488GA F IF WB 0.1 mg
Sheep anti Rabbit IgG:DyLight®680 STAR36D680GA F IF WB 0.1 mg
Sheep anti Rabbit IgG:Dylight®800 STAR36D800GA F IF WB 0.1 mg

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