SAMHD1 antibody | OTI1F6

Mouse anti SAMHD1

Product Type
PrecisionAb Monoclonal
Clone
OTI1F6
Isotype
IgG1
Format
Purified
Specificity
SAMHD1

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VMA00139
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SDS Safety Datasheet SDS
WB 100 µl loader
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Mouse anti Human SAMHD1 antibody, clone OTI1F6 recognizes the deoxynucleoside triphosphate triphosphohydrolase SAMHD1, also known as SAM domain and HD domain-containing protein 1, dNTPase, dendritic cell-derived IFNG-induced protein, deoxynucleoside triphosphate triphosphohydrolase SAMHD1 and monocyte protein 5.

SAMHD1 may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in the SAMHD1 gene have been associated with Aicardi-Goutieres syndrome (provided by RefSeq, Mar 2010).

Mouse anti Human SAMHD1 antibody detects a band of 72 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
PrecisionAb Antibodies

Target Species
Human
Western Blotting
Anti SAMHD1 detects a band of approximately 72 kDa in Raji cell lysates.
Product Form
Purified IgG - liquid.
Preparation
Mouse monoclonal antibody purified by affinity chromatography from ascites.
Buffer Solution
Phosphate buffered saline.
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
1% Bovine Serum Albumin
50% Glycerol
Immunogen
Full length recombinant human SAMHD1 (NP_056289) produced in HEK293T cells
Regulatory
For research purposes only.
Guarantee
12 months from date of despatch.
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories.

Store undiluted at -20oC, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

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Goat anti Mouse IgG (H/L):HRP STAR207P WB 2 ml loader
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Description Goat anti Mouse IgG (H/L):HRP

UniProt
Q9Y3Z3
Entrez Gene
SAMHD1
GO Terms
GO:0005634 nucleus
GO:0016787 hydrolase activity
GO:0045087 innate immune response
GO:0045088 regulation of innate immune response
GO:0051607 defense response to virus
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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