SAMHD1 antibody | OTI1F6
Mouse anti Human SAMHD1 antibody recognizes the deoxynucleoside triphosphate triphosphohydrolase SAMHD1, also known as SAM domain and HD domain-containing protein 1, dNTPase, dendritic cell-derived IFNG-induced protein, deoxynucleoside triphosphate triphosphohydrolase SAMHD1 and monocyte protein 5.
SAMHD1 may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in the SAMHD1 gene have been associated with Aicardi-Goutieres syndrome (provided by RefSeq, Mar 2010).
Mouse anti Human SAMHD1 antibody detects a band of 72 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
SAMHD1 may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in the SAMHD1 gene have been associated with Aicardi-Goutieres syndrome (provided by RefSeq, Mar 2010).
Mouse anti Human SAMHD1 antibody detects a band of 72 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
Product Details
- Target Species
- Human
- Western Blotting
- Anti SAMHD1 detects a band of approximately 72 kDa in Raji cell lysates.
- Product Form
- Purified IgG - liquid
- Preparation
- Mouse monoclonal antibody purified by affinity chromatography from ascites.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
1% Bovine Serum Albumin
50% Glycerol - Immunogen
- Full length recombinant human SAMHD1 (NP_056289) produced in HEK293T cells
Storage Information
- Storage
- Store undiluted at -20oC, avoiding repeated freeze thaw cycles.
- Guarantee
- As supplied, 12 months from date of despatch.
More Information
- UniProt
- Q9Y3Z3 Related reagents
- Entrez Gene
- SAMHD1 Related reagents
- GO Terms
- GO:0005634 nucleus
- GO:0016787 hydrolase activity
- GO:0045087 innate immune response
- GO:0045088 regulation of innate immune response
- GO:0051607 defense response to virus
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories.
- Regulatory
- For research purposes only
Applications of SAMHD1 antibody
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting | 1/1000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
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Secondary Antibodies Available
| Description | Product Code | Applications | Pack Size | List Price | Quantity |
|---|---|---|---|---|---|
| Goat anti Mouse IgG (H/L):HRP | STAR207P | WB | 2 ml |
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