S100 antibody | 6G1
When glial cells are damaged, S100 protein is leaked into the extracellular matrix and cerebrospinal fluid, further releasing into the bloodstream. As such, S100 protein can be used as a sensitive and reliable marker for nervous system damage, such as after brain damage or acute stroke.
Mouse anti Human S100 Protein antibody, clone 6G1 recognizes both S100a (alpha-beta) and S100b (beta-beta).
Mouse anti Human S100 Protein antibody, clone 6G1 is sensitive to EDTA and other bivalent-binding agents. Better performance can be obtained in the presence of 5mM CaCl2 in assay buffers.
- Target Species
- Product Form
- Purified IgG - liquid
- Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
0.09% Sodium Azide
- Human brain S100 protein.
- Approx. Protein Concentrations
- IgG concentration 1 mg/ml
- Fusion Partners
- Spleen cells from immunised BALB/c mice were fused with cells of the Sp2/0 myeloma cell line.
- Store at +4oC or at -20oC if preferred.
This product should be stored undiluted.
Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
- 12 months from date of despatch
- For research purposes only
Applications of S100 antibody
|Application Name||Verified||Min Dilution||Max Dilution|
Secondary Antibodies Available
Product Specific References
References for S100 antibody
Paus, E. et al. (2011) TD-11 workshop report: characterization of monoclonal antibodies to S100 proteins.
Tumour Biol. 32 (1): 1-12.
Wang, Q. et al. (2012) Evaluation of human brain damage in fatalities due to extreme environmental temperature by quantification of basic fibroblast growth factor (bFGF), glial fibrillary acidic protein (GFAP), S100β and single-stranded DNA (ssDNA) immunoreactivities.
Forensic Sci Int. 219 (1-3): 259-64.