RUVBL2 antibody | OTI1A6

Mouse anti RUVBL2

Product Type
PrecisionAb Monoclonal
Clone
OTI1A6
Isotype
IgG1
Format
Purified
Specificity
RUVBL2

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VMA00186
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
WB 100 µl loader
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Mouse anti Human RUVBL2 antibody, clone OTI1A6 recognizes RUVBL2, also known as 48 kDa TATA box-binding protein-interacting protein, 48 kDa TBP-interacting protein, 51 kDa erythrocyte cytosolic protein, ECP-51, INO80 complex subunit J, RuvB (E coli homolog)-like 2, TAP54-beta, TIP60-associated protein 54-beta, erythrocyte cytosolic protein, 51-KD, repressing pontin 52, reptin52 protein and ruvB-like 2.

The RUVBL2 gene encodes the second human homologue of the bacterial RuvB gene. Bacterial RuvB protein is a DNA helicase essential for homologous recombination and DNA double-strand break repair. Functional analysis showed that RUVBL2 product has both ATPase and DNA helicase activities. RUVBL2 is physically linked to the CGB/LHB gene cluster on chromosome 19q13.3, and is very close (55 nt) to the LHB gene, in the opposite orientation (provided by RefSeq, Jul 2008).

Mouse anti Human RUVBL2 antibody, clone OTI1A6 detects a band of 48 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
PrecisionAb Antibodies

Target Species
Human
Western Blotting
Anti RUVBL2 detects a band of approximately 48 kDa in K562 cell lysates.
Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse
Rat
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Preparation
Mouse monoclonal antibody purified by affinity chromatography from ascites.
Buffer Solution
Phosphate buffered saline.
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
1% Bovine Serum Albumin
50% Glycerol
Immunogen
Recombinant protein fragment corresponding to amino acids 113-370 of human RUVBL2 (NP_006657) produced in E. coli
Regulatory
For research purposes only.
Guarantee
12 months from date of despatch.
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories.

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

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Description Goat anti Mouse IgG (H/L):HRP

UniProt
Q9Y230
Entrez Gene
RUVBL2
GO Terms
GO:0051082 unfolded protein binding
GO:0003684 damaged DNA binding
GO:0006457 protein folding
GO:0016020 membrane
GO:0004003 ATP-dependent DNA helicase activity
GO:0005524 ATP binding
GO:0005737 cytoplasm
GO:0006281 DNA repair
GO:0006310 DNA recombination
GO:0006350 transcription
GO:0042802 identical protein binding
GO:0016363 nuclear matrix
GO:0035267 NuA4 histone acetyltransferase complex
GO:0040008 regulation of growth
GO:0043967 histone H4 acetylation
GO:0043968 histone H2A acetylation
GO:0045449 regulation of transcription
GO:0071339 MLL1 complex
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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