RPL14 antibody | AB02/1A6
Mouse anti RPL14
- Product Type
- PrecisionAb Monoclonal
- Clone
- AB02/1A6
- Isotype
- IgG1
- Format
- Purified
- Specificity
- RPL14
Mouse anti RPL14 antibody recognizes 60S ribosomal protein L14, also known as CAG-ISL 7. RPL14 encodes a component of the large ribosomal subunit (Huang et al. 2006). The small and large ribosomal subunits play different roles within protein translation. The small subunit decodes the genetic message, while the large subunit catalyzes the formation of peptide bonds (Gregory et al. 2019). Alteration of RPL14 has been identified in esophageal squamous cell carcinomas and has been suggested as an early marker of this cancer type (Huang et al. 2006). More generally, genetic abnormalities that affect ribosome biogenesis result in a range of clinical phenotypes, such as Diamond-Blackfan anemia. Acquired mutations in ribosome function have been broadly linked to human cancers (Narla and Ebert 2010). |
- Target Species
- Human
- Western Blotting
- Mouse anti RPL14 detects a band of approximately 25 kDa in HeLa cell lysates
- Species Cross-Reactivity
-
Target Species Cross Reactivity Mouse Rat - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - Liquid
- Preparation
- Mouse monoclonal antibody affinity purified on Protein G from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide
- Immunogen
- E. coli-derived recombinant protein of amino acids 1-215 of human RPL14
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Fusion Partners
- Spleen cells from immunised BALB/c mice were fused with cells of the mouse SP2/0 myeloma cell line
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
Western Blotting | 1/2000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
---|---|---|---|---|---|---|---|
Goat anti Mouse IgG (H/L):HRP | STAR207P | WB | 2 ml | Log in | |||
List Price | Your Price | ||||||
Log in | |||||||
Description | Goat anti Mouse IgG (H/L):HRP |
VMA00955
100005857If you cannot find the batch/lot you are looking for please contact our technical support team for assistance.
Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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