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RPL14 antibody | AB02/1A6

Mouse anti RPL14

Product Type
PrecisionAb Monoclonal
Clone
AB02/1A6
Isotype
IgG1
Format
Purified
Specificity
RPL14

Product Code Applications Pack Size List Price Your Price Qty
VMA00955
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
WB 100 µl loader
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loader

Mouse anti RPL14 antibody recognizes 60S ribosomal protein L14, also known as CAG-ISL 7. RPL14 encodes a component of the large ribosomal subunit (Huang et al. 2006). The small and large ribosomal subunits play different roles within protein translation. The small subunit decodes the genetic message, while the large subunit catalyzes the formation of peptide bonds (Gregory et al. 2019). Alteration of RPL14 has been identified in esophageal squamous cell carcinomas and has been suggested as an early marker of this cancer type (Huang et al. 2006). More generally, genetic abnormalities that affect ribosome biogenesis result in a range of clinical phenotypes, such as Diamond-Blackfan anemia. Acquired mutations in ribosome function have been broadly linked to human cancers (Narla and Ebert 2010). PrecisionAb Antibodies

Target Species
Human
Western Blotting
Mouse anti RPL14 detects a band of approximately 25 kDa in HeLa cell lysates
Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse
Rat
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - Liquid
Preparation
Mouse monoclonal antibody affinity purified on Protein G from tissue culture supernatant
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide
Immunogen
E. coli-derived recombinant protein of amino acids 1-215 of human RPL14
Approx. Protein Concentrations
IgG concentration 1.0 mg/ml
Fusion Partners
Spleen cells from immunised BALB/c mice were fused with cells of the mouse SP2/0 myeloma cell line
Regulatory
For research purposes only
Guarantee
12 months from date of despatch
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories

Store undiluted at -20°C, avoiding repeated freeze thaw cycles

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/2000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Description Product Code Applications Pack Size List Price Your Price Quantity
Goat anti Mouse IgG (H/L):HRP STAR207P WB 2 ml loader
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Description Goat anti Mouse IgG (H/L):HRP

UniProt
P50914
Entrez Gene
RPL14

VMA00955

100005857

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