RING1 antibody

Mouse anti RING1

Product Type
PrecisionAb Monoclonal
Isotype
IgG1
Format
Purified
Specificity
RING1

Product Code Applications Pack Size List Price Your Price Qty
VMA00223
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SDS Safety Datasheet SDS
WB 100 µl loader
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Mouse anti Human RING1 antibody recognizes the E3 ubiquitin-protein ligase RING1, also known as E3 ubiquitin-protein ligase RING1, polycomb complex protein RING1 and really interesting new gene 1 protein.

RING1 belongs to the RING finger family, members of which encode proteins characterized by a RING domain, a zinc-binding motif related to the zinc finger domain. The gene product can bind DNA and can act as a transcriptional repressor. It is associated with the multimeric polycomb group protein complex. The gene product interacts with the polycomb group proteins BMI1, EDR1, and CBX4, and colocalizes with these proteins in large nuclear domains. It interacts with the CBX4 protein via its glycine-rich C-terminal domain. The gene maps to the HLA class II region, where it is contiguous with the RING finger genes FABGL and HKE4 (provided by RefSeq, Jul 2008).

Mouse anti Human RING1 antibody detects a band of 54 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
PrecisionAb Antibodies

Target Species
Human
Western Blotting
Anti RING1 detects a band of approximately 54 kDa in Jurkat cell lysates.
Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse
Rat
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Preparation
Mouse monoclonal antibody prepared by affinity chromatography on Protein G from ascites.
Buffer Solution
Phosphate buffered saline.
Preservative Stabilisers
0.09% Sodium Azide (NaN3).
Immunogen
Recombinant protein corresponding to amino acids 79-263 of human RING1 expressed in E. coli
Regulatory
For research purposes only.
Guarantee
12 months from date of despatch.
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories.

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

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Goat anti Mouse IgG (H/L):HRP STAR207P WB 2 ml loader
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Description Goat anti Mouse IgG (H/L):HRP

UniProt
Q06587
Entrez Gene
RING1
GO Terms
GO:0005515 protein binding
GO:0005737 cytoplasm
GO:0006350 transcription
GO:0008270 zinc ion binding
GO:0016564 transcription repressor activity
GO:0016607 nuclear speck
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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