RAP1A/B antibody | AB01/2C6.10.4
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WB ResetMouse anti RAP1A/B
- Product Type
- PrecisionAb Monoclonal
- Clone
- AB01/2C6.10.4
- Isotype
- IgG2b
- Format
- Purified
- Specificity
- RAP1A/B
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| Mouse anti Human RAP1A/B antibody recognizes the Ras-related protein Rap-1b, also known as GTP-binding protein smg p21B, Ras family small GTP binding protein RAP1B or small GTP binding protein. RAP1B gene encodes a member of the RAS-like small GTP-binding protein superfamily. Members of this family regulate multiple cellular processes including cell adhesion and growth and differentiation. This protein localizes to cellular membranes and has been shown to regulate integrin-mediated cell signaling. This protein also plays a role in regulating outside-in signaling in platelets. Alternate splicing results in multiple transcript variants. Pseudogenes of RAP1B are found on chromosomes 3, 5, 6 and 9 (provided by RefSeq, Oct 2011). Mouse anti Human RAP1A/B antibody detects a band of 21 kDa. The antibody has been extensively validated for western blotting using whole cell lysates. |
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- Target Species
- Human
- Western Blotting
- Anti RAP1A/B detects a band of approximately 21 kDa in K562 cell lysates.
- Species Cross-Reactivity
-
Target Species Cross Reactivity Mouse Rat - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Preparation
- Mouse monoclonal antibody purified by affinity chromatography on Protein G from tissue culture supernatant.
- Buffer Solution
- Phosphate buffered saline.
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3).
- Immunogen
- E. coli-derived recombinant human RAP1A/B (amino acids 1 - 184)
- Regulatory
- For research purposes only.
- Guarantee
- 12 months from date of despatch.
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories.
Store undiluted at -20oC, avoiding repeated freeze thaw cycles.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting |  |
1/1000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
|---|---|---|---|---|---|---|---|
| Goat anti Mouse IgG (H/L):HRP | STAR207P | WB | 2 ml |
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| List Price | Your Price | ||||||
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| Description | Goat anti Mouse IgG (H/L):HRP | ||||||
- UniProt
- P62834
- P61224
- Entrez Gene
- RAP1B
- RAP1A
- GO Terms
- GO:0005886 plasma membrane
- GO:0005515 protein binding
- GO:0003924 GTPase activity
- GO:0007596 blood coagulation
- GO:0005829 cytosol
- GO:0005525 GTP binding
- GO:0006112 energy reserve metabolic process
- GO:0050796 regulation of insulin secretion
- GO:0019003 GDP binding
- View More GO Terms
- GO:0000186 activation of MAPKK activity
- GO:0048011 nerve growth factor receptor signaling pathway
View more products with RAP1A/B specificity
Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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