RANTES antibody | OTI2A7

100% Secure


Mouse anti RANTES

Product Type
PrecisionAb Monoclonal
Clone
OTI2A7
Isotype
IgG1
Format
Purified
Product Code Applications Pack Size List Price Quantity
VMA00692
Datasheet
WB
MSDS
100 µl loader

Mouse anti Human RANTES antibody recognizes RANTES, also known as C-C motif chemokine 5, beta-chemokine RANTES and CCL5.

CCL5 is a member of the CC subfamily of chemokines that functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It acts as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5) and suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor (provided by RefSeq, Jul 2013).

Mouse anti Human RANTES antibody detects a band of 10 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.

Product Details

Target Species
Human
Western Blotting
Mouse anti RANTES detects a band of approximately 10 kDa in differentiated THP-1 cells stimulated for 16 hrs with lipopolysaccharide (LPS)
Product Form
Purified IgG - Liquid
Preparation
Mouse monoclonal antibody affinity purified on immunogen from ascites
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide
Immunogen
HEK293-dervied full length human recombinant protein of human RANTES

Storage Information

Storage
Store undiluted at -20°C, avoiding repeated freeze thaw cycles
Guarantee
12 months from date of despatch

More Information

UniProt
P13501
Entrez Gene
CCL5
GO Terms
GO:0009615 response to virus
GO:0007155 cell adhesion
GO:0004871 signal transducer activity
GO:0005615 extracellular space
GO:0006874 cellular calcium ion homeostasis
GO:0006887 exocytosis
GO:0006955 immune response
GO:0006968 cellular defense response
GO:0006979 response to oxidative stress
GO:0007267 cell-cell signaling
GO:0008009 chemokine activity
GO:0042056 chemoattractant activity
GO:0045071 negative regulation of viral genome replication
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories.
Regulatory
For research purposes only

Applications of RANTES antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Secondary Antibodies Available

Description Product Code Applications Pack Size List Price Quantity
Goat anti Mouse IgG (H/L):HRP STAR207P WB 2 ml