Qki antibody | CD01/1C3

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Mouse anti Qki

Product Type
PrecisionAb Monoclonal
Clone
CD01/1C3
Isotype
IgG1
Format
Purified
Product Code Applications Pack Size List Price Quantity
VMA00911
Datasheet
WB
SDS
100 µl loader

Mouse anti QKI antibody recognizes protein quaking, also known as Hqk and Hqk1.

The mRNA-binding protein QKI regulates mRNA stability, nuclear retention, RNA transportation and translational modulation, by binding to the QKI response element (QRE) of target mRNAs. Many cancer-related genes including Ras, Jun, and p53 contain QREs (Lu et al. 2014). QKI functions as a tumor suppressor in glioma and other malignancies, and is a major regulator of stemness of neural stem cells (Shingu et al. 2017).

Product Details

Target Species
Human
Western Blotting
Mouse anti QKI detects a band of approximately 41 kDa in K562 cell lysates
Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse
Rat
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - Liquid
Preparation
Mouse monoclonal antibody affinity purified on Protein G from tissue culture supernatant
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide
Immunogen
E. coli-derived recombinant protein of amino acids 1-341 of human QKI
Approx. Protein Concentrations
IgG concentration 1.0 mg/ml
Fusion Partners
Spleen cells from immunised BALB/c mice were fused with cells of the mouse SP2/0 myeloma cell line

Storage Information

Storage
Store undiluted at -20°C, avoiding repeated freeze thaw cycles
Guarantee
12 months from date of despatch

More Information

UniProt
Q96PU8
Entrez Gene
QKI
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories
Regulatory
For research purposes only

Applications of Qki antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Secondary Antibodies Available

Description Product Code Applications Pack Size List Price Quantity
Goat anti Mouse IgG (H/L):HRP STAR207P WB 2 ml

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