PSMA6 antibody | OTI7C2

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Anti PSMA6 Antibody, clone OTI7C2 (PrecisionAb Monoclonal Antibody) thumbnail image 1

Anti PSMA6 Antibody, clone OTI7C2 (PrecisionAb Monoclonal Antibody) gallery image 1 — Western blot analysis of whole cell lysates probed with PSMA6 antibody (**VMA00472**) followed by detection with HRP conjugated Goat anti Mouse IgG antibody (1/10,000, STAR207P) and visualized on the ChemiDoc MP with 7 second exposure. Arrow points to PSMA6 (molecular weight 26 kDa).

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Mouse anti PSMA6

Product Type: PrecisionAb Monoclonal
Clone: OTI7C2
Isotype: IgG1
Format: Purified
Specificity: PSMA6

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Product Code Applications Pack Size List Price Your Price Qty

List Price	Your Price
VMA00472 Datasheet Datasheet SDS SDS	WB	100 µl		Log in	Get Quote
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Mouse anti Human PSMA6 antibody recognizes the PSMA6, also known as 27 kDa prosomal protein, PROS-27, macropain iota chain, multicatalytic endopeptidase complex iota chain, prosomal P27K protein, proteasome iota chain, proteasome subunit alpha type-6 or proteasome subunit iota.

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMA6 gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Multiple transcript variants encoding several different isoforms have been found for PSMA6. A pseudogene has been identified on the Y chromosome (provided by RefSeq, Aug 2013).

Mouse anti Human PSMA6 antibody detects a band of 26 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.

Target Species: Human
Western Blotting: Anti PSMA6 detects a band of approximately 26 kDa in Jurkat cell lysate.
Species Cross-Reactivity: Target Species Cross Reactivity

Mouse

Rat; N.B. Antibody reactivity and working conditions may vary between species.
Product Form: Purified IgG - liquid
Preparation: Purified IgG prepared by affinity chromatography on Protein G from ascites.
Buffer Solution: Phosphate buffered saline.
Preservative Stabilisers: 0.09% Sodium Azide (NaN₃)
1% Bovine Serum Albumin
50% Glycerol.
Immunogen: Full length recombinant protein of human PSMA6 produced in E. Coli
Regulatory: For research purposes only.
Guarantee: 12 months from date of despatch.
Acknowledgements: PrecisionAb is a trademark of Bio-Rad Laboratories.

Target Species	Cross Reactivity
Mouse
Rat

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

Application Name	Verified	Min Dilution	Max Dilution
Western Blotting		1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Description	Product Code	Applications	Pack Size	Your Price
Goat anti Mouse IgG (H/L):HRP	STAR207P	WB	2 ml	Log in	Get Quote
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Description	Goat anti Mouse IgG (H/L):HRP

UniProt: P60900
Entrez Gene: PSMA6
GO Terms: GO:0000082 G1/S transition of mitotic cell cycle; GO:0000084 S phase of mitotic cell cycle; GO:0000216 M/G1 transition of mitotic cell cycle; GO:0003723 RNA binding; GO:0006915 apoptosis; GO:0005739 mitochondrion; GO:0004298 threonine-type endopeptidase activity; GO:0005844 polysome; GO:0006521 regulation of cellular amino acid metabolic process; View More GO Terms; GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; GO:0016032 viral reproduction; GO:0016071 mRNA metabolic process; GO:0042981 regulation of apoptosis; GO:0016363 nuclear matrix; GO:0019773 proteasome core complex, alpha-subunit complex; GO:0030017 sarcomere; GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; GO:0035639 purine ribonucleoside triphosphate binding; GO:0050727 regulation of inflammatory response; GO:0051059 NF-kappaB binding; GO:0051092 positive regulation of NF-kappaB transcription factor activity; GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle