Mouse anti Human prostate specific antigen antibody, clone P4 recognises prostate specific antigen (PSA), a serine protease produced by prostatic epithelial cells, which is also known as kallikrein 3. Serum PSA levels have been correlated with the stage of prostatic cancer, and have been used to monitor residual tumour levels and disease progression.
Mouse anti Human prostate specific antigen antibody, clone P4 has also been known by the clone designation BGN/PSA6.
- Target Species
- Product Form
- Purified IgG - liquid
- Purified IgG prepared by affinity chromatography on Protein G.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Human Prostate Specific Antigen isolated from pooled human seminal fluid.
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
- 18 months from date of despatch.
- Entrez Gene
- GO Terms
serine-type endopeptidase activity
negative regulation of angiogenesis
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of Prostate Specific Antigen antibody
|Immunohistology - Paraffin 1
- 1This product requires antigen retrieval using heat treatment prior to staining of paraffin sections.
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.
- Western Blotting
- Under non-reducing conditions a PSA triplet is observed at approx 30kDa. Under reducing conditions a doublet can be observed.
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Secondary Antibodies Available
Useful Reagents Available