PPP2CB antibody | AB02/4B4

Mouse anti PPP2CB

Product Type
PrecisionAb Monoclonal

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Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
IP WB 100 µl loader
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Mouse anti PPP2CB antibody recognizes serine/threonine-protein phosphatase 2A catalytic subunit beta isoform, also known as PP2A-beta.

PPP2CB is a major serine/threonine phosphatase with regulatory roles in numerous cellular pathways (Eydmann and Knowles 1997). During mammalian oocyte development, PPP2CB upregulation is involved with the meiotic arrest phenotype and female infertility (Su et al. 2012). PPP2CB has been identified as a potential gene involved with pathogenesis of Parkinson's disease when mutated (Guo et al. 2018). PPP2CB is also a tumor suppressor, and targeting of PPP2CB via miRNA-1246 has been found to initiate pro-inflammatory responses in mesenchymal stem/stromal cells (Bott et al. 2017).
PrecisionAb Antibodies

Target Species
Western Blotting
Mouse anti PPP2CB antibody detects a band of approximately 34 kDa in HEK293 cell lysates
Species Cross-Reactivity
Target SpeciesCross Reactivity
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - Liquid
Mouse monoclonal antibody affinity purified on Protein G from tissue culture supernatant
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide
E. coli-derived recombinant protein of amino acids 1-309 of human PPP2CB
Approx. Protein Concentrations
IgG concentration 1.0 mg/ml
Fusion Partners
Spleen cells from immunised BALB/c mice were fused with cells of the mouse SP2/0 myeloma cell line
For research purposes only
12 months from date of despatch
PrecisionAb is a trademark of Bio-Rad Laboratories

Store undiluted at -20°C, avoiding repeated freeze thaw cycles

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

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Goat anti Mouse IgG (H/L):HRP STAR207P WB 2 ml loader
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Description Goat anti Mouse IgG (H/L):HRP

Entrez Gene
GO Terms
GO:0000159 protein phosphatase type 2A complex
GO:0000775 chromosome, centromeric region
GO:0000922 spindle pole
GO:0046872 metal ion binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0006470 protein dephosphorylation
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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