POLR2E antibody | CD01/1F2
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WB ResetMouse anti POLR2E
- Product Type
- PrecisionAb Monoclonal
- Clone
- CD01/1F2
- Isotype
- IgG1
- Format
- Purified
- Specificity
- POLR2E
Antibody Quality and Performance Guarantee
| Mouse anti POLR2E antibody recognizes DNA-directed RNA polymerases I, II, and III subunit RPABC1, also known as polymerase II polypeptide E. DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA. The rs3787016 polymorphism of POLR2E has been suggested as a potential biomarker for cancer disposition (Chen et al. 2018). |
|
- Target Species
- Human
- Western Blotting
- Mouse anti POLR2E antibody detects a band of approximately 23 kDa in HEK293 cell lysates
- Species Cross-Reactivity
-
Target Species Cross Reactivity Mouse Rat - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - Liquid
- Preparation
- Mouse monoclonal antibody affinity purified on Protein G from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide
- Immunogen
- E. coli-derived recombinant protein of amino acids 1-210 of human POLR2E
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Fusion Partners
- Spleen cells from immunised BALB/c mice were fused with cells of the mouse SP2/0 myeloma cell line
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories
Store undiluted at -20°C, avoiding repeated freeze thaw cycles
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting |  |
1/1000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
|---|---|---|---|---|---|---|---|
| Goat anti Mouse IgG (H/L):HRP | STAR207P | WB | 2 ml |
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| List Price | Your Price | ||||||
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| Description | Goat anti Mouse IgG (H/L):HRP | ||||||
- UniProt
- P19388
- Entrez Gene
- POLR2E
- GO Terms
- GO:0000398 nuclear mRNA splicing, via spliceosome
- GO:0003677 DNA binding
- GO:0003899 DNA-directed RNA polymerase activity
- GO:0005665 DNA-directed RNA polymerase II, core complex
- GO:0006283 transcription-coupled nucleotide-excision repair
- GO:0006367 transcription initiation from RNA polymerase II promoter
- GO:0006368 transcription elongation from RNA polymerase II promoter
- GO:0006370 mRNA capping
- GO:0006385 transcription elongation from RNA polymerase III promoter
- View More GO Terms
- GO:0006386 termination of RNA polymerase III transcription
- GO:0016032 viral reproduction
- GO:0044419 interspecies interaction between organisms
- GO:0050434 positive regulation of viral transcription
VMA00880
100004567
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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