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Podoplanin antibody | AB01/1B6

Mouse anti Podoplanin

Product Type
PrecisionAb Monoclonal

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Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
WB 100 µl loader
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Mouse anti Podoplanin antibody recognizes podoplanin, also known as aggrus, glycoprotein 36, and T1-alpha.

Podoplanin is a mucin-type transmembrane receptor required for correct formation of the lungs and lymphatic system during embryogenesis. Although discovered in the kidney, Podoplanin is expressed in numerous other human tissues including skeletal muscle, heart, placenta, and lung (Sikorska et al. 2019). Podoplanin regulates the activity of proteins including Rho and ezrin, and affects tumor cell motility, invasion and metastasis. Expression of Podoplanin is induced by tumor promoters, and Podoplanin has been suggested as a cancer biomarker and therapeutic agent (Krishnan et al. 2013). Specifically, inhibitors of Podoplanin or the Podoplanin-mediated signaling pathway have been suggested as treatments for small-cell lung cancer (Takahashi et al. 2015).
PrecisionAb Antibodies

Target Species
Western Blotting
Mouse anti podoplanin antibody detects a band of approximately 39 kDa in HEK293 cell lysates
Species Cross-Reactivity
Target SpeciesCross Reactivity
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - Liquid
Mouse monoclonal antibody affinity purified on Protein G from tissue culture supernatant
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide
E. coli-derived recombinant protein of amino acids 1-162 of human podoplanin
Approx. Protein Concentrations
IgG concentration 1.0 mg/ml
Fusion Partners
Spleen cells from immunised BALB/c mice were fused with cells of the mouse SP2/0 myeloma cell line
For research purposes only
12 months from date of despatch
PrecisionAb is a trademark of Bio-Rad Laboratories

Store undiluted at -20°C, avoiding repeated freeze thaw cycles

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

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Goat anti Mouse IgG (H/L):HRP STAR207P WB 2 ml loader
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Description Goat anti Mouse IgG (H/L):HRP

Entrez Gene
GO Terms
GO:0000902 cell morphogenesis
GO:0001946 lymphangiogenesis
GO:0005887 integral to plasma membrane
GO:0008360 regulation of cell shape
GO:0031258 lamellipodium membrane
GO:0031527 filopodium membrane
GO:0031528 microvillus membrane
GO:0032587 ruffle membrane



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