PI-3 Kinase Subunit Gamma antibody | OTI6D1

ISO 9001 Quality Assurance Manufacturing | Print

Anti PI-3 Kinase Subunit Gamma Antibody, clone OTI6D1 (PrecisionAb Monoclonal Antibody) thumbnail image 1

Anti PI-3 Kinase Subunit Gamma Antibody, clone OTI6D1 (PrecisionAb Monoclonal Antibody) thumbnail image 2

Anti PI-3 Kinase Subunit Gamma Antibody, clone OTI6D1 (PrecisionAb Monoclonal Antibody) gallery image 1 — Western blot analysis of PI-3 kinase subunit gamma expression in K562 whole cell lysate probed with Mouse anti PI-3 Kinase Subunit Gamma antibody (**VMA00277**) followed by detection with HRP conjugated Goat anti Mouse IgG (1/10,000 STAR207P) and visualized on the ChemiDoc MP with a 300 second exposure. Arrow points at PI-3 kinase subunit gamma.

Anti PI-3 Kinase Subunit Gamma Antibody, clone OTI6D1 (PrecisionAb Monoclonal Antibody) gallery image 2 — Western blot analysis of PI-3 kinase subunit gamma expression in Jurkat whole cell lysate probed with Mouse anti PI-3 Kinase Subunit Gamma antibody (**VMA00277**) followed by detection with HRP conjugated Goat anti Mouse IgG (1/10,000 STAR207P) and visualized on the ChemiDoc MP with a 60 second exposure. Arrow points at PI-3 kinase subunit gamma.

Filter by Application:

Mouse anti PI-3 Kinase Subunit Gamma

Product Type: PrecisionAb Monoclonal
Clone: OTI6D1
Isotype: IgG2a
Format: Purified
Specificity: PI-3 Kinase Subunit Gamma

Quick Links:

Secondary Antibodies
Applications
Storage Information
Batch/Lot Specific Datasheets

Antibody Quality and Performance Guarantee

Unrivaled Technical Support

Product Code Applications Pack Size List Price Your Price Qty

List Price	Your Price
VMA00277 Datasheet Datasheet SDS SDS	WB	100 µl		Log in	Get Quote
	Log in

Mouse anti Human PI-3 kinase subunit gamma antibody recognizes the phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, also known as 1-phosphatidylinositol 3-kinase, phosphatidylinositol 3 kinase gamma, p110 gamma, phosphatidylinositol 3-kinase catalytic 110-kD gamma, phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, phosphatidylinositol-4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma, phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, phosphoinositide-3-kinase gamma catalytic subunit, ptdIns-3-kinase subunit gamma, ptdIns-3-kinase subunit p110-gamma and serine/threonine protein kinase PIK3CG.

A product of the PIK3CG gene, PI-3 kinase subunit gamma belongs to the pi3/pi4-kinase family of proteins. The gene product is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. The gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias. Several transcript variants encoding the same protein have been found for PIK3CG (provided by RefSeq, Sep 2013).

Mouse anti Human PI-3 kinase subunit gamma isoform antibody detects a band of 126 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.

Target Species: Human
Western Blotting: Anti PI-3 Kinase subunit gamma detects a band of approximately 126 kDa in K562 cell lysates.
Product Form: Purified IgG - liquid
Preparation: Mouse monoclonal antibody purified by affinity chromatography from ascites.
Buffer Solution: Phosphate buffered saline.
Preservative Stabilisers: 0.09% Sodium Azide (NaN₃)
1% Bovine Serum Albumin
50% Glycerol
Immunogen: Full length recombinant human PI-3 kinase subunit gamma (NP_002640) produced in HEK293T cells
Regulatory: For research purposes only.
Guarantee: 12 months from date of despatch.
Acknowledgements: PrecisionAb is a trademark of Bio-Rad Laboratories.

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

Application Name	Verified	Min Dilution	Max Dilution
Western Blotting		1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Description	Product Code	Applications	Pack Size	Your Price
Goat anti Mouse IgG (H/L):HRP	STAR207P	WB	2 ml	Log in	Get Quote
List Price	Your Price
	Log in
Description	Goat anti Mouse IgG (H/L):HRP

UniProt: P48736
Entrez Gene: PIK3CG
GO Terms: GO:0005515 protein binding; GO:0005524 ATP binding; GO:0005942 phosphatidylinositol 3-kinase complex; GO:0007186 G-protein coupled receptor protein signaling pathway; GO:0016303 1-phosphatidylinositol-3-kinase activity; GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity; GO:0048015 phosphatidylinositol-mediated signaling; GO:0030168 platelet activation