Peroxiredoxin 6 antibody

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Mouse anti Peroxiredoxin 6

Product Type
PrecisionAb Monoclonal
Isotype
IgG2b
Format
Purified
Product Code Applications Pack Size List Price Quantity
VMA00583
Datasheet
WB
MSDS
100 µl loader

Mouse anti Human peroxiredoxin 6 antibody recognizes peroxiredoxin 6, also known as 1-Cys PRX, 1-Cys peroxiredoxin, acidic calcium-independent phospholipase A2, PRDX6 or non-selenium glutathione peroxidase.

The protein encoded by PRDX6 gene is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional enzyme with two distinct active sites. It is involved in redox regulation of the cell; it can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. It may play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury (provided by RefSeq, Jul 2008).

Mouse anti Human peroxiredoxin 6 antibody detects a band of 25 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.

Product Details

Target Species
Human
Western Blotting
Anti peroxiredoxin 6 detects a band of approximately 25 kDa in HeLa cell lysates
Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Preparation
Mouse monoclonal antibody purified by affinity chromatography on Protein G from ascites
Buffer Solution
HEPES buffered saline
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
1% Bovine Serum Albumin
<50% Glycerol
Immunogen
E. coli-derived recombinant human peroxiredoxin 6

Storage Information

Storage
Store undiluted at -20oC, avoiding repeated freeze thaw cycles.
Guarantee
12 months from date of despatch

More Information

UniProt
P30041
Entrez Gene
PRDX6
GO Terms
GO:0005515 protein binding
GO:0005764 lysosome
GO:0004623 phospholipase A2 activity
GO:0005829 cytosol
GO:0055114 oxidation-reduction process
GO:0045454 cell redox homeostasis
GO:0009395 phospholipid catabolic process
GO:0016023 cytoplasmic membrane-bounded vesicle
GO:0051920 peroxiredoxin activity
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories.
Regulatory
For research purposes only

Applications of Peroxiredoxin 6 antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Secondary Antibodies Available

Description Product Code Applications Pack Size List Price Quantity
Goat anti Mouse IgG (H/L):HRP STAR207P WB 2 ml