NKX3-1 antibody | UMAB195

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Mouse anti NKX3-1

Product Type
PrecisionAb Monoclonal
Clone
UMAB195
Isotype
IgG2a
Format
Purified
Product Code Applications Pack Size List Price Quantity
VMA00387
Datasheet
WB
MSDS
100 µl loader

Mouse anti Human NKX3-1 antibody recognizes homeobox protein NKX3-1, also known as NK homeobox, family 3, A, NK3 transcription factor homolog A, NK3 transcription factor related, locus 1 and homeobox protein NKX3.1.

Encoded by the NKX3-1 gene, this transcription factor functions as a negative regulator of epithelial cell growth in prostate tissue. Aberrant expression of NKX3-1 is associated with prostate tumor progression. Alternate splicing results in multiple transcript variants of NKX3-1 (provided by RefSeq, Jan 2012).

Mouse anti NKX3-1 antibody detects a band of 32 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.

Product Details

Target Species
Human
Western Blotting
Anti NKX3-1 detects a band of approximately 32 kDa in LNCaP cell lysates
Product Form
Purified IgG - liquid
Preparation
Mouse monoclonal antibody purified by affinity chromatography from ascites
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
1% Bovine Serum Albumin
50% Glycerol
Immunogen
Full length recombinant human NKX3-1 (NP_006158) produced in E.coli

Storage Information

Storage
Store undiluted at -20oC, avoiding repeated freeze thaw cycles.
Guarantee
As supplied, 12 months from date of despatch.

More Information

UniProt
Q99801 Related reagents
Entrez Gene
NKX3-1 Related reagents
GO Terms
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005634 nucleus
GO:0016564 transcription repressor activity
GO:0030284 estrogen receptor activity
GO:0030331 estrogen receptor binding
GO:0032582 negative regulation of gene-specific transcription
GO:0043565 sequence-specific DNA binding
GO:0071899 negative regulation of estrogen receptor binding
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories.
Regulatory
For research purposes only

Applications of NKX3-1 antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Secondary Antibodies Available

Description Product Code Applications Pack Size List Price Quantity
Goat anti Mouse IgG (H/L):HRP STAR207P WB 2 ml

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