NFE2L2 gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been found for NFE2L2 (provided by RefSeq, Jan 2012).
Mouse anti Human NFE2L2 antibody detects a band of 68 kDa. The antibody has been extensively validated for western blotting using whole cell lysates. The mouse anti Human NFE2L2 antibody is available with a positive control lysate, in a smaller trial size, and as a standalone antibody.
- Target Species
- Western Blotting
- Anti NFE2L2 detects a band of approximately 68 kDa in HeLa cell lysates
- Species Cross-Reactivity
Target Species Cross Reactivity Mouse Rat
- N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Mouse monoclonal antibody prepared by affinity chromatography on Protein G from ascites
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Recombinant protein corresponding to amino acids 356-589 of human NFE2L2 expressed in E. coli
- Store undiluted at -20oC, avoiding repeated freeze thaw cycles.
- As supplied, 12 months from date of despatch.
- Entrez Gene
- GO Terms
- GO:0005886 plasma membrane
- GO:0003700 sequence-specific DNA binding transcription factor activity
- GO:0005829 cytosol
- GO:0005634 nucleus
- GO:0005813 centrosome
- GO:0006366 transcription from RNA polymerase II promoter
- GO:0019904 protein domain specific binding
- GO:0043565 sequence-specific DNA binding
- GO:0046983 protein dimerization activity
- PrecisionAb is a trademark of Bio-Rad Laboratories.
- For research purposes only
Applications of NFE2L2 antibody
|Application Name||Verified||Min Dilution||Max Dilution|
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
Secondary Antibodies Available
|Description||Product Code||Applications||Pack Size||List Price||Quantity|
|Goat anti Mouse IgG (H/L):HRP||STAR207P||WB||2 ml|