NDRG1 antibody | GH01/4A7

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WB ResetMouse anti NDRG1
- Product Type
- PrecisionAb Monoclonal
- Clone
- GH01/4A7
- Isotype
- IgG1
- Format
- Purified
- Specificity
- NDRG1
Mouse anti NDRG1 antibody recognizes protein NDRG1, also known as DRG-1 and RTP. NDRG1 is a stress-response protein induced by hypoxia and cell differentiation signals. It has been found to act as a tumor suppressor in a variety of cancer types, suppressing migration, invasion, and metastasis by regulating epithelial-mesenchymal transition (EMT) or downregulating ErbB receptors (Dong et al. 2019). However, NDRG1 may have an oncogenic role in other cancerous conditions, making its role in cancer more complex (Du et al. 2018). For example, overexpression of NDRG1 has been found to be associated with elevated rates of metastasis and mortality in patients with breast cancer (Sevinsky et al. 2018). |
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- Target Species
- Human
- Western Blotting
- Mouse anti NDRG1 detects a band of approximately 45 kDa in HT-1080 cell lysates
- Product Form
- Purified IgG - Liquid
- Preparation
- Mouse monoclonal antibody affinity purified on Protein G from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide
- Immunogen
- E. coli-derived recombinant protein of amino acids 1-394 of human NDRG1
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Fusion Partners
- Spleen cells from immunised BALB/c mice were fused with cells of the mouse SP2/0 myeloma cell line
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
Western Blotting | ![]() |
1/1000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
---|---|---|---|---|---|---|---|
Goat anti Mouse IgG (H/L):HRP | STAR207P | WB | 2 ml |
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List Price | Your Price | ||||||
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Description | Goat anti Mouse IgG (H/L):HRP |
- UniProt
- Q92597
- Entrez Gene
- NDRG1
- GO Terms
- GO:0005886 plasma membrane
- GO:0005515 protein binding
- GO:0005634 nucleus
- GO:0005737 cytoplasm
- GO:0010038 response to metal ion
- GO:0015630 microtubule cytoskeleton
VMA00950

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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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