Myoglobin antibody | 4E2
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Mouse anti Human Myoglobin (Cardiac)
- Product Type
- Monoclonal Antibody
- Clone
- 4E2
- Isotype
- IgG1
- Specificity
- Myoglobin
- Region
- (CARDIAC)
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| Mouse anti Human Myoglobin (Cardiac) antibody, clone 4E2 recognizes human cardiac myoglobin, a single-chain globular 17kDa protein containing a heme prosthetic group. It is responsible for the storage and movement of oxygen in muscle tissue. Myoglobin is released from injured muscle tissue, thus making it a sensitive marker for all muscle injury. It is commonly used in combination with troponin as a marker for myocardial damage in heart attacks. It is filtered by the kidneys, but is a potential cause of renal failure as it is toxic to the renal tubular epithelium. |
- Target Species
- Human
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- <0.1% Sodium Azide (NaN3)
- Immunogen
- Human cardiac myoglobin.
- Approx. Protein Concentrations
- IgG concentration 1.0mg/ml
- Fusion Partners
- Spleen cells from immunised Balb/c were fused with cells of the Sp2/0 myeloma cell line.
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| ELISA |  |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- RRID
- AB_2235127
- UniProt
- P02144
- Entrez Gene
- MB
- GO Terms
- GO:0005344 oxygen transporter activity
- GO:0020037 heme binding
View more products with MYOGLOBIN specificity
Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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