MRPL28 antibody | AB04/3B11
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WB ResetMouse anti MRPL28
- Product Type
- PrecisionAb Monoclonal
- Clone
- AB04/3B11
- Isotype
- IgG1
- Format
- Purified
- Specificity
- MRPL28
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| Mouse anti MRPL28 antibody recognizes 39S ribosomal protein L28, mitochondrial, also known as L28mt, MRP-L28, and melanoma antigen p15. MRPL28 is a nuclearly encoded, mitochondrial protein required for correct function of the mitochindrial ribosome, and for synthesis of mitochondrially encoded proteins. Knockdown of MRPL28 in pancreatic cancer cells has been shown to decrease mitochondrial activity and inhibit cell growth (Chen et al. 2009). Hypermethylation of the MRPL28 gene locus has been suggested as a risk factor for asthma development (Gunawardhana et al. 2014). It has also been suggested that differences in the MRPL28 gene may play a role in obesity by altering fat oxidization (Lin et al. 2013). |
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- Target Species
- Human
- Western Blotting
- Mouse anti MRPL28 detects a band of approximately 28 kDa in HEK293 cell lysates
- Product Form
- Purified IgG - Liquid
- Preparation
- Mouse monoclonal antibody affinity purified on Protein G from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide
- Immunogen
- E. coli-derived recombinant protein of amino acids 1-256 of human MRPL28
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Fusion Partners
- Spleen cells from immunised BALB/c mice were fused with cells of the mouse SP2/0 myeloma cell line
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories
Store undiluted at -20°C, avoiding repeated freeze thaw cycles
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting |  |
1/1000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
|---|---|---|---|---|---|---|---|
| Goat anti Mouse IgG (H/L):HRP | STAR207P | WB | 2 ml |
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| List Price | Your Price | ||||||
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| Description | Goat anti Mouse IgG (H/L):HRP | ||||||
- UniProt
- Q13084
- Entrez Gene
- MRPL28
- GO Terms
- GO:0003735 structural constituent of ribosome
- GO:0005761 mitochondrial ribosome
- GO:0006412 translation
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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