MBP antibody | V/h5

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Mouse anti Human MBP

Product Type
Monoclonal Antibody
Clone
V/h5
Isotype
IgG1
Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
6420-2704 E R 0.2 mg
Mouse anti MBP antibody, clone V/h5 recognizes an epitope toward the N-terminal region of myelin basic protein reacting with an epitope between amino acids 45 and 91. Myelin basic protein is a major component of the myelin membrane which in turn forms a multi layered insulating sheath round oligodendrocytes and Schwann cells in the nervous system, acting to increase the efficiency of signal transduction.

Product Details

Target Species
Human
Species Cross-Reactivity
Target SpeciesCross Reactivity
Rabbit
Guinea Pig
Sheep
Bovine
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Preparation
Purified IgG prepared by affinity chromatography on Protein A
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
Immunogen
N-terminal fragment of human MBP (residues 1-118) produced by BNPS-skatole cleavage of pure human MBP, injected coupled to BSA using carbodiimide.
Approx. Protein Concentrations
IgG concentration 1.0 mg/ml

Storage Information

Storage
Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted.
Avoid repeated freezing and thawing as this may denature the antibody.
Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life
18 months from date of despatch.

More Information

UniProt
P02686 Related reagents
Entrez Gene
MBP Related reagents
Regulatory
For research purposes only

Applications of MBP antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
ELISA
Radioimmunoassays
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.

Product Specific References

References for MBP antibody

  1. Elfman, L. et al. (1986) Rat and mouse monoclonal antibodies to human myelin basic protein.
    J Neurochem. 46 (2): 509-15.