IL-6 antibody | MQ2-39C3

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Rat anti Human Interleukin-6:Biotin

Rat anti Human Interleukin-6

Product Type: Monoclonal Antibody
Clone: MQ2-39C3
Isotype: IgG2a

Product Code	Applications	Pack Size	Your Price	List Price	Quantity
1012108 Datasheet	E SDS	0.5 mg	Log in		Get Quote
1012101 Datasheet	E SDS	0.5 mg	Log in		Get Quote

Rat anti Human interleukin-6 antibody, clone MQ2-39C3 recognizes human interleukin 6, a cytokine and potent inducer of the acute phase response.

Product Details

Target Species: Human
Product Form: Purified IgG conjugated to Biotin - liquid
Product Form: Purified IgG - liquid
Buffer Solution: Phosphate buffered saline
Buffer Solution: Borate buffered saline
Preservative Stabilisers: <0.1% Sodium Azide (NaN₃)
Preservative Stabilisers: None present
Approx. Protein Concentrations: 0.5 mg/ml
Approx. Protein Concentrations: IgG concentration 0.5 mg/ml

Storage Information

Storage: This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.

Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Storage: Store at -20^oC only.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Guarantee: 12 months from date of despatch
Guarantee: 12 months from date of despatch

More Information

UniProt: P05231
Entrez Gene: IL6
GO Terms: GO:0001781 neutrophil apoptosis; GO:0002384 hepatic immune response; GO:0002446 neutrophil mediated immunity; GO:0002548 monocyte chemotaxis; GO:0002675 positive regulation of acute inflammatory response; GO:0002690 positive regulation of leukocyte chemotaxis; GO:0006953 acute-phase response; GO:0005125 cytokine activity; GO:0005138 interleukin-6 receptor binding; GO:0005615 extracellular space; GO:0005896 interleukin-6 receptor complex; GO:0006959 humoral immune response; GO:0008083 growth factor activity; GO:0050830 defense response to Gram-positive bacterium; GO:0050829 defense response to Gram-negative bacterium; GO:0008285 negative regulation of cell proliferation; GO:0010574 regulation of vascular endothelial growth factor production; GO:0010888 negative regulation of lipid storage; GO:0045727 positive regulation of translation; GO:0030168 platelet activation; GO:0031018 endocrine pancreas development; GO:0031175 neuron projection development; GO:0032494 response to peptidoglycan; GO:0032722 positive regulation of chemokine production; GO:0032755 positive regulation of interleukin-6 production; GO:0032966 negative regulation of collagen biosynthetic process; GO:0033138 positive regulation of peptidyl-serine phosphorylation; GO:0042102 positive regulation of T cell proliferation; GO:0042517 positive regulation of tyrosine phosphorylation of Stat3 protein; GO:0043066 negative regulation of apoptosis; GO:0043193 positive regulation of gene-specific transcription; GO:0043410 positive regulation of MAPKKK cascade; GO:0045079 negative regulation of chemokine biosynthetic process; GO:0045599 negative regulation of fat cell differentiation; GO:0045669 positive regulation of osteoblast differentiation; GO:0045765 regulation of angiogenesis; GO:0045768 positive regulation of anti-apoptosis; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0048661 positive regulation of smooth muscle cell proliferation; GO:0050871 positive regulation of B cell activation; GO:0051024 positive regulation of immunoglobulin secretion; GO:0051091 positive regulation of transcription factor activity; GO:0051384 response to glucocorticoid stimulus; GO:0051607 defense response to virus; GO:0070091 glucagon secretion; GO:0070102 interleukin-6-mediated signaling pathway
Regulatory: For research purposes only

Applications of IL-6 antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

Application Name	Verified	Min Dilution	Max Dilution
ELISA
ELISA

Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

ELISA: Biotinylated clone MQ2-39C3 may be used in a direct ELISA or as the detection reagent in a sandwich ELISA with clone MQ2-13A5 as the capture antibody.

Secondary Antibodies Available

Description	Product Code	Applications	Pack Size	Your Price	Quantity
Goat anti Rat IgG:Alk. Phos. (Mouse Adsorbed)	STAR131A	C E P WB	1 ml	Log in	Get Quote
Goat anti Rat IgG:Biotin (Mouse Adsorbed)	STAR131B	C E IF P WB	0.5 mg	Log in	Get Quote
Rabbit F(ab')2 anti Rat IgG:Dylight®800	STAR16D800GA	F IF WB	0.1 mg	Log in	Get Quote
Rabbit F(ab')2 anti Rat IgG:FITC	STAR17B	F	1 mg	Log in	Get Quote
Rabbit F(ab')2 anti Rat IgG:HRP	STAR21B	C E P RE	1 mg	Log in	Get Quote
Goat F(ab')2 anti Rat IgG:FITC (Mouse Adsorbed)	STAR69	F	0.5 ml	Log in	Get Quote
Goat anti Rat IgG:Dylight®800 (Mouse Adsorbed)	STAR71D800GA	F IF WB	0.1 mg	Log in	Get Quote
Goat anti Rat IgG:HRP (Mouse Adsorbed)	STAR72	C E P	0.5 mg	Log in	Get Quote
Goat F(ab')2 anti Rat IgG:RPE (Mouse Adsorbed)	STAR73	F	0.5 ml	Log in	Get Quote

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