IL-13 antibody | B-P6

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Mouse anti Human Interleukin-13:FITC

Product Type
Monoclonal Antibody
Clone
B-P6
Isotype
IgG1
Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
MCA2791F F* 100 Tests
Mouse anti Human CD13 antibody, clone B-P6 recognizes human interleukin-13 (IL-13), a 12.5 kDa immunoregulatory cytokine produced primarily by activated T helper type 2 (Th2) cells, and also by mast cells and NK cells.

IL-13 induces the stimulation of B cell proliferation, antibody production and plays an important role in the induction of the pathophysiological features of allergic asthma, independently of Immunoglobulin E (IgE) and eosinophils (Wills-Karp et al. 1998).

Product Details

Target Species
Human
Product Form
Purified IgG - liquid
Preparation
Purified IgG prepared by ion exchange chromatography
Buffer Solution
TRIS buffered saline
Preservative Stabilisers
0.02% Sodium Azide (NaN3)
1% Bovine Serum Albumin
Immunogen
Recombinant human IL-13.

Storage Information

Storage
Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted.
This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life
18 months from date of despatch.

More Information

UniProt
P35225 Related reagents
Entrez Gene
IL13 Related reagents
GO Terms
GO:0007165 signal transduction
GO:0005125 cytokine activity
GO:0005615 extracellular space
GO:0005625 soluble fraction
GO:0006928 cellular component movement
GO:0006954 inflammatory response
GO:0006955 immune response
GO:0007267 cell-cell signaling
Regulatory
For research purposes only

Applications of IL-13 antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Flow Cytometry 1
  1. 1Membrane permeabilisation is required for this application. Bio-Rad recommends the use of Leucoperm™ (Product Code BUF09) for this purpose.
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Flow Cytometry
Use 10ul of the suggested working dilution to label 1x106 cells in 100ul.

Negative Isotype Controls Available

Description Product Code Pack Size Applications List Price Quantity
Mouse IgG1 Negative Control:FITC MCA928F 100 Tests F

Useful Reagents Available

Description Product Code Pack Size Applications List Price Quantity
Human Seroblock BUF070A 50 Test F
Human Seroblock BUF070B 200 Test F

Product Specific References

Further Reading

  1. Wills-Karp, M. et al. (1998) Interleukin-13: central mediator of allergic asthma.
    Science. 282 (5397): 2258-61.