IGF-I antibody | M23/ILG1-001
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Mouse anti Human Insulin-Like Growth Factor I
- Product Type
- Monoclonal Antibody
- Clone
- M23/ILG1-001
- Isotype
- IgG1
- Specificity
- IGF-I
Antibody Quality and Performance Guarantee
| Mouse anti human IGF-I, clone M23/ILG1-001, recognizes insulin-like growth factor 1, also knowm as somatomedin C. It shows minimal cross-reactivity with IGF-II, Proinsulin, MSF and Insulin. IGF-I is a secreted endocrine hormone that acts as the primary mediator for the effects of growth hormone. |
- Target Species
- Human
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Carrier Free
- Yes
- Immunogen
- Biosynthetic IGF-I
- Affinity
- 108-109 L/mole.
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| ELISA |  |
1/10 000 | 1/100 000 |
| Radioimmunoassays | |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.
- Synonyms
- Insulin-Like Growth Factor I
- RRID
- AB_619079
- UniProt
- P05019
- Entrez Gene
- IGF1
- GO Terms
- GO:0006260 DNA replication
- GO:0002576 platelet degranulation
- GO:0005158 insulin receptor binding
- GO:0005159 insulin-like growth factor receptor binding
- GO:0005179 hormone activity
- GO:0006916 anti-apoptosis
- GO:0006928 cellular component movement
- GO:0007265 Ras protein signal transduction
- GO:0007517 muscle organ development
- View More GO Terms
- GO:0008083 growth factor activity
- GO:0009441 glycolate metabolic process
- GO:0010552 positive regulation of gene-specific transcription from RNA polymerase II promoter
- GO:0014068 positive regulation of phosphatidylinositol 3-kinase cascade
- GO:0014834 satellite cell maintenance involved in skeletal muscle regeneration
- GO:0014896 muscle hypertrophy
- GO:0014904 myotube cell development
- GO:0014911 positive regulation of smooth muscle cell migration
- GO:0046326 positive regulation of glucose import
- GO:0016942 insulin-like growth factor binding protein complex
- GO:0048015 phosphatidylinositol-mediated signaling
- GO:0030168 platelet activation
- GO:0031093 platelet alpha granule lumen
- GO:0034392 negative regulation of smooth muscle cell apoptosis
- GO:0035630 bone mineralization involved in bone maturation
- GO:0040014 regulation of multicellular organism growth
- GO:0042523 positive regulation of tyrosine phosphorylation of Stat5 protein
- GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway
- GO:0045445 myoblast differentiation
- GO:0045669 positive regulation of osteoblast differentiation
- GO:0045725 positive regulation of glycogen biosynthetic process
- GO:0045740 positive regulation of DNA replication
- GO:0045821 positive regulation of glycolysis
- GO:0045840 positive regulation of mitosis
- GO:0046579 positive regulation of Ras protein signal transduction
- GO:0048146 positive regulation of fibroblast proliferation
- GO:0048661 positive regulation of smooth muscle cell proliferation
- GO:0050679 positive regulation of epithelial cell proliferation
- GO:0051450 myoblast proliferation
5345-0304
1602
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