GSTO1 antibody | AB01/1C5

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Mouse anti GSTO1

Product Type
PrecisionAb Monoclonal
Product Code Applications Pack Size List Price Quantity
100 µl loader

Mouse anti GSTO1 antibody recognizes glutathione S-transferase omega-1, also known as GSTO1-1, MMA(V) reductade and SPG-R.

GSTO1 is an Omega class member of the cytosolic glutathione transferase (GST) superfamily, and is able to catalyze several redox reactions (Board et al. 2000), contributing to regulation of inflammation and oxidative stress in a variety of organ systems (Fernando et al. 2018). In response to LPS, GSTO1 has a pro-inflammatory role in models of inflammation, colitis and obesity (Menon et al. 2017), and has been suggested as a target for anti-inflammatory intervention (Menon et al. 2014). A critical role of GSTO1 in maintaining the phenotype of breast cancer stem cells has been identified (Lu et al. 2017), and specific polymorphisms are associated with response to bladder cancer treatment (Deng et al. 2015).

Product Details

Target Species
Western Blotting
Mouse anti GSTO1 detects a band of approximately 27 kDa in HEK293 cell lysates
Product Form
Purified IgG - Liquid
Mouse monoclonal antibody affinity purified on Protein G from tissue culture supernatant
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide
E. coli-derived recombinant protein of amino acids 1-241 of human GSTO1
Approx. Protein Concentrations
IgG concentration 1.0 mg/ml
Fusion Partners
Spleen cells from immunised BALB/c mice were fused with cells of the mouse SP2/0 myeloma cell line

Storage Information

Store undiluted at -20°C, avoiding repeated freeze thaw cycles
12 months from date of despatch

More Information

Entrez Gene
GO Terms
GO:0004364 glutathione transferase activity
GO:0005829 cytosol
GO:0006805 xenobiotic metabolic process
GO:0016656 monodehydroascorbate reductase (NADH) activity
PrecisionAb is a trademark of Bio-Rad Laboratories
For research purposes only

Applications of GSTO1 antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Secondary Antibodies Available

Description Product Code Applications Pack Size List Price Quantity
Goat anti Mouse IgG (H/L):HRP STAR207P WB 2 ml

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