GSTO1 antibody | AB01/1C5

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Anti GSTO1 Antibody, clone AB01/1C5 (PrecisionAb Monoclonal Antibody) thumbnail image 1

Anti GSTO1 Antibody, clone AB01/1C5 (PrecisionAb Monoclonal Antibody) gallery image 1 — Western blot analysis of whole cell lysates probed with GSTO1 antibody (1/1,000, **VMA00930**) followed by detection with HRP conjugated Goat anti Mouse IgG (1/10,000, STAR207P) and visualized on the ChemiDoc MP. Arrow points to GSTO1 (molecular weight 27 kDa)

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Mouse anti GSTO1

Product Type: PrecisionAb Monoclonal
Clone: AB01/1C5
Isotype: IgG2b
Format: Purified
Specificity: GSTO1

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VMA00930 Datasheet Datasheet SDS SDS	WB	100 µl		Log in	Get Quote
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Mouse anti GSTO1 antibody recognizes glutathione S-transferase omega-1, also known as GSTO1-1, MMA(V) reductade and SPG-R.

GSTO1 is an Omega class member of the cytosolic glutathione transferase (GST) superfamily, and is able to catalyze several redox reactions (Board et al. 2000), contributing to regulation of inflammation and oxidative stress in a variety of organ systems (Fernando et al. 2018). In response to LPS, GSTO1 has a pro-inflammatory role in models of inflammation, colitis and obesity (Menon et al. 2017), and has been suggested as a target for anti-inflammatory intervention (Menon et al. 2014). A critical role of GSTO1 in maintaining the phenotype of breast cancer stem cells has been identified (Lu et al. 2017), and specific polymorphisms are associated with response to bladder cancer treatment (Deng et al. 2015).

Target Species: Human
Western Blotting: Mouse anti GSTO1 detects a band of approximately 27 kDa in HEK293 cell lysates
Product Form: Purified IgG - Liquid
Preparation: Mouse monoclonal antibody affinity purified on Protein G from tissue culture supernatant
Buffer Solution: Phosphate buffered saline
Preservative Stabilisers: 0.09% Sodium Azide
Immunogen: E. coli-derived recombinant protein of amino acids 1-241 of human GSTO1
Approx. Protein Concentrations: IgG concentration 1.0 mg/ml
Fusion Partners: Spleen cells from immunised BALB/c mice were fused with cells of the mouse SP2/0 myeloma cell line
Regulatory: For research purposes only
Guarantee: 12 months from date of despatch
Acknowledgements: PrecisionAb is a trademark of Bio-Rad Laboratories

Store undiluted at -20°C, avoiding repeated freeze thaw cycles

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

Application Name	Verified	Min Dilution	Max Dilution
Western Blotting			1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Description	Product Code	Applications	Pack Size	Your Price
Goat anti Mouse IgG (H/L):HRP	STAR207P	WB	2 ml	Log in	Get Quote
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Description	Goat anti Mouse IgG (H/L):HRP

UniProt: P78417
Entrez Gene: GSTO1
GO Terms: GO:0004364 glutathione transferase activity; GO:0005829 cytosol; GO:0006805 xenobiotic metabolic process; GO:0016656 monodehydroascorbate reductase (NADH) activity