GSTK1 antibody | AB02/2F8

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Mouse anti GSTK1

Product Type
PrecisionAb Monoclonal
Clone
AB02/2F8
Isotype
IgG2b
Format
Purified
Product Code Applications Pack Size List Price Quantity
VMA00818
Datasheet
WB
SDS
100 µl loader

Mouse anti GSTK1 antibody recognizes glutathione S-transferase kappa 1, also known as hGSTK1.

GSTK1 belongs to the GST superfamily of enzymes involved with detoxification of noxious compounds and protection from oxidative damage. The kappa class of GSTs (GSTK) are mitochondrial and peroxisomal (Munyampundu et al. 2016). GST activity in tumor cells may be related to their resistance to chemotherapeutic drugs, and identifying GST polymorphisms could help guide personalized cancer therapy (Waś et al. 2018). GSTK1 is crucial for maintenance of mitochondrial function and homeostasis (Munyampundu et al. 2016). GSTK1 has been suggested as a potential biomarker for type 2 diabetes (Deng et al. 2019).

Product Details

Target Species
Human
Western Blotting
Mouse anti GSTK1 antibody detects a band of approximately 23 kDa in HEK293 cell lysates
Product Form
Purified IgG - Liquid
Preparation
Mouse monoclonal antibody affinity purified on Protein G from tissue culture supernatant
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide
Immunogen
E. coli-derived recombinant protein of amino acids 1-226 of human GSTK1
Approx. Protein Concentrations
IgG concentration 1.0 mg/ml
Fusion Partners
Spleen cells from immunised BALB/c mice were fused with cells of the mouse SP2/0 myeloma cell line

Storage Information

Storage
Store undiluted at -20°C, avoiding repeated freeze thaw cycles
Guarantee
12 months from date of despatch

More Information

UniProt
Q9Y2Q3
Entrez Gene
GSTK1
GO Terms
GO:0004364 glutathione transferase activity
GO:0005777 peroxisome
GO:0042802 identical protein binding
GO:0015035 protein disulfide oxidoreductase activity
GO:0030288 outer membrane-bounded periplasmic space
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories
Regulatory
For research purposes only

Applications of GSTK1 antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Secondary Antibodies Available

Description Product Code Applications Pack Size List Price Quantity
Goat anti Mouse IgG (H/L):HRP STAR207P WB 2 ml

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