GSTK1 antibody | AB02/2F8
Mouse anti GSTK1 antibody recognizes glutathione S-transferase kappa 1, also known as hGSTK1.
GSTK1 belongs to the GST superfamily of enzymes involved with detoxification of noxious compounds and protection from oxidative damage. The kappa class of GSTs (GSTK) are mitochondrial and peroxisomal (Munyampundu et al. 2016). GST activity in tumor cells may be related to their resistance to chemotherapeutic drugs, and identifying GST polymorphisms could help guide personalized cancer therapy (Waś et al. 2018). GSTK1 is crucial for maintenance of mitochondrial function and homeostasis (Munyampundu et al. 2016). GSTK1 has been suggested as a potential biomarker for type 2 diabetes (Deng et al. 2019).
GSTK1 belongs to the GST superfamily of enzymes involved with detoxification of noxious compounds and protection from oxidative damage. The kappa class of GSTs (GSTK) are mitochondrial and peroxisomal (Munyampundu et al. 2016). GST activity in tumor cells may be related to their resistance to chemotherapeutic drugs, and identifying GST polymorphisms could help guide personalized cancer therapy (Waś et al. 2018). GSTK1 is crucial for maintenance of mitochondrial function and homeostasis (Munyampundu et al. 2016). GSTK1 has been suggested as a potential biomarker for type 2 diabetes (Deng et al. 2019).
Product Details
- Target Species
- Human
- Western Blotting
- Mouse anti GSTK1 antibody detects a band of approximately 23 kDa in HEK293 cell lysates
- Product Form
- Purified IgG - Liquid
- Preparation
- Mouse monoclonal antibody affinity purified on Protein G from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide
- Immunogen
- E. coli-derived recombinant protein of amino acids 1-226 of human GSTK1
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Fusion Partners
- Spleen cells from immunised BALB/c mice were fused with cells of the mouse SP2/0 myeloma cell line
Storage Information
- Storage
- Store undiluted at -20°C, avoiding repeated freeze thaw cycles
- Guarantee
- 12 months from date of despatch
More Information
- UniProt
- Q9Y2Q3
- Entrez Gene
- GSTK1
- GO Terms
- GO:0004364 glutathione transferase activity
- GO:0005777 peroxisome
- GO:0042802 identical protein binding
- GO:0015035 protein disulfide oxidoreductase activity
- GO:0030288 outer membrane-bounded periplasmic space
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories
- Regulatory
- For research purposes only
Applications of GSTK1 antibody
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting | 1/1000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
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Secondary Antibodies Available
| Description | Product Code | Applications | Pack Size | List Price | Quantity |
|---|---|---|---|---|---|
| Goat anti Mouse IgG (H/L):HRP | STAR207P | WB | 2 ml |
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