Glutamate Decarboxylase 2 antibody | 114.4E8
Mouse anti human GAD2, Clone 114.4E8, recognizes glutamate decarboxylase 2, also known as GAD65 due to its molecular weight. GAD2 is an enzyme responsible for catalyzing the production of gamma-aminobutyric acid (GABA) from glutamic acid. It is an autoantibody and autoreactive T cell target in insulin-dependent diabetes.
- Target Species
- Product Form
- Purified IgG - liquid
- Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Carrier Free
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
- Shelf Life
- 18 months from date of despatch.
- Q05329 Related reagents
- Entrez Gene
- GAD2 Related reagents
- GO Terms
- GO:0000139 Golgi membrane
- GO:0005515 protein binding
- GO:0042136 neurotransmitter biosynthetic process
- GO:0004351 glutamate decarboxylase activity
- GO:0005829 cytosol
- GO:0006540 glutamate decarboxylation to succinate
- GO:0007269 neurotransmitter secretion
- GO:0030054 cell junction
- GO:0030170 pyridoxal phosphate binding
- GO:0042734 presynaptic membrane
- GO:0061202 clathrin sculpted gamma-aminobutyric acid transport vesicle membrane
- For research purposes only
Applications of Glutamate Decarboxylase 2 antibody
|Application Name||Verified||Min Dilution||Max Dilution|
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Copyright © 2018 Bio-Rad Antibodies (formerly AbD Serotec)