GFAP antibody | GF-05

Mutations in the GFAP gene may result in presentation of Alexander disease (ALXDRD), a rare neurological condition affecting infants and characterized by myelination failure leading to early death (Brenner et al. 2001)
Product Details
- Target Species
- Human
- Species Cross-Reactivity
-
Target Species Cross Reactivity Cynomolgus monkey - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein G
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Immunogen
- Native GFAP purified from human brain.
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
Storage Information
- Storage
- Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted.
Avoid repeated freezing and thawing as this may denature the antibody.
Should this product contain a precipitate we recommend microcentrifugation before use. - Guarantee
- 12 months from date of despatch
More Information
Applications of GFAP antibody
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
ELISA | |||
Western Blotting |
Secondary Antibodies Available
Product Specific References
References for GFAP antibody
-
Burbaeva, G.Sh. et al. (2007) Systemic neurochemical alterations in schizophrenic brain: glutamate metabolism in focus.
Neurochem Res. 32: 1434-44. -
Gil-Perotin, S. et al. (2009) Ultrastructure of the subventricular zone in Macaca fascicularis and evidence of a mouse-like migratory stream.
J Comp Neurol. 514: 533-54. -
Wei, P. et al. (2013) Serum GFAP autoantibody as an ELISA-detectable glioma marker.
Tumour Biol. 34 (4): 2283-92. -
Garbayo, E. et al. (2016) Brain delivery of microencapsulated GDNF induces functional and structural recovery in parkinsonian monkeys.
Biomaterials. 110: 11-23. -
Martinez-Valbuena, M. et al. (2019) Amylin as a potential link between type 2 diabetes and alzheimer disease.
Ann Neurol. 86 (4): 539-51.
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