FTO antibody | OTI4A1
KO Validated
Mouse anti FTO
- Product Type
- PrecisionAb Monoclonal
- Clone
- OTI4A1
- Isotype
- IgG1
- Format
- Purified
- Specificity
- FTO
Antibody Quality and Performance Guarantee
| Mouse anti Human FTO antibody recognizes FTO, also known as AlkB homolog 9, alpha-ketoglutarate-dependent dioxygenase FTO, fat mass and obesity-associated protein and protein fto. FTO is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of FTO is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. FTO has a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes (provided by RefSeq, Jul 2011). Mouse anti Human FTO antibody detects a band of 60 kDa. The antibody has been extensively validated for western blotting using whole cell lysates. |
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- Target Species
- Human
- Western Blotting
- Mouse anti FTO detects a band of approximately 60 kDa in HepG2 cell lysates
- Species Cross-Reactivity
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Target Species Cross Reactivity Mouse - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - Liquid
- Preparation
- Mouse monoclonal antibody affinity purified on Protein G from ascites
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide
1% Bovine Serum Albumin - Immunogen
- HEK293-derived full length recombinant protein of human FTO
- Approx. Protein Concentrations
- IgG concentration 0.5 mg/ml
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories.
Store undiluted at -20°C, avoiding repeated freeze thaw cycles
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting |  |
1/1000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
|---|---|---|---|---|---|---|---|
| Goat anti Mouse IgG (H/L):HRP | STAR207P | WB | 2 ml |
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| List Price | Your Price | ||||||
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| Description | Goat anti Mouse IgG (H/L):HRP | ||||||
- UniProt
- Q9C0B1
- Entrez Gene
- FTO
- GO Terms
- GO:0005634 nucleus
- GO:0006307 DNA dealkylation involved in DNA repair
- GO:0008198 ferrous iron binding
- GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
- GO:0035515 oxidative RNA demethylase activity
- GO:0035516 oxidative DNA demethylase activity
- GO:0035552 oxidative single-stranded DNA demethylation
- GO:0035553 oxidative single-stranded RNA demethylation
- GO:0042245 RNA repair
- View More GO Terms
- GO:0043734 DNA-N1-methyladenine dioxygenase activity
VMA00723
170727
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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