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FAF1 antibody

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Anti FAF1 Antibody (PrecisionAb Monoclonal Antibody) thumbnail image 1
Anti FAF1 Antibody (PrecisionAb Monoclonal Antibody) gallery image 1
Western blot analysis of whole cell lysates probed with FAF1 antibody (VMA00236) followed by detection with HRP conjugated Goat anti Mouse IgG (1/10000, STAR207P) and visualized on the ChemiDoc MP with 14 second exposure. Arrow points to FAF1 (molecular weight 74 kDa).

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WB

Mouse anti FAF1

Product Type
PrecisionAb Monoclonal
Isotype
IgG2b
Format
Purified
Specificity
FAF1

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Product Code Applications Pack Size List Price Your Price Qty
VMA00236
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
WB 100 µl loader
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loader
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Mouse anti Human FAF1 antibody recognizes the FAS-associated factor 1, also known as TNFRSF6-associated factor 1, UBX domain protein 3A and UBX domain-containing protein 12.

Interaction of Fas ligand (TNFSF6) with the FAS antigen (TNFRSF6) mediates programmed cell death, also called apoptosis, in a number of organ systems. The protein encoded by FAF1 gene binds to FAS antigen and can initiate apoptosis or enhance apoptosis initiated through FAS antigen. Initiation of apoptosis by the protein encoded by FAF1 requires a ubiquitin-like domain but not the FAS-binding domain (provided by RefSeq, Jul 2008).

Mouse anti Human FAF1 antibody detects a band of 74 kDa. The antibody has been extensively validated for western blotting using whole cell lysates. 		PrecisionAb Antibodies

Target Species
Human
Western Blotting
Anti FAF1 detects a band of approximately 74 kDa in K562 cell lysates
Product Form
Purified IgG - liquid
Preparation
Mouse monoclonal antibody prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
Immunogen
Recombinant human FAF1
Regulatory
For research purposes only
Guarantee
12 months from date of despatch
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories.

Store undiluted at -20oC, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Description Product Code Applications Pack Size List Price Your Price Quantity
Goat anti Mouse IgG (H/L):HRP STAR207P WB 2 ml loader
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loader
Description Goat anti Mouse IgG (H/L):HRP

UniProt
Q9UNN5
Entrez Gene
FAF1
GO Terms
GO:0006915 apoptosis
GO:0005829 cytosol
GO:0007253 cytoplasmic sequestering of NF-kappaB
GO:0019887 protein kinase regulator activity
GO:0031072 heat shock protein binding
GO:0019901 protein kinase binding
GO:0031265 CD95 death-inducing signaling complex
GO:0031334 positive regulation of protein complex assembly
GO:0042176 regulation of protein catabolic process
GO:0043065 positive regulation of apoptosis
GO:0043161 proteasomal ubiquitin-dependent protein catabolic process
GO:0048471 perinuclear region of cytoplasm
GO:0051059 NF-kappaB binding
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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