EXPORTIN-1 antibody

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Mouse anti EXPORTIN-1

Product Type
PrecisionAb Monoclonal
Isotype
IgG2b
Format
Purified
Product Code Applications Pack Size List Price Quantity
VMA00085
Datasheet
WB
MSDS
100 µl loader

Mouse anti Human exportin-1 antibody recognizes exportin-1, also known as Exp1, XPO1 and chromosome region maintenance 1 protein homolog.

Exportin-1 mediates leucine-rich nuclear export signal (NES)-dependent protein transport and specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1 (provided by RefSeq, Jul 2008).

Mouse anti Human exportin-1 antibody detects a band of 112 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.

Product Details

Target Species
Human
Western Blotting
Anti exportin-1 detects a band of approximately 112 kDa in Jurkat cell lysates.
Product Form
Purified IgG - liquid
Preparation
Mouse monoclonal antibody purified by affinity chromatography on Protein G from tissue culture supernatant
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
Immunogen
E. Coli derived recombinant protein, aa 932-1071 of human exportin-1

Storage Information

Storage
Store undiluted at -20oC, avoiding repeated freeze thaw cycles.
Guarantee
As supplied, 12 months from date of despatch.

More Information

UniProt
O14980 Related reagents
Entrez Gene
XPO1 Related reagents
GO Terms
GO:0005515 protein binding
GO:0000236 mitotic prometaphase
GO:0000776 kinetochore
GO:0003723 RNA binding
GO:0030529 ribonucleoprotein complex
GO:0005829 cytosol
GO:0005635 nuclear envelope
GO:0005642 annulate lamellae
GO:0005730 nucleolus
GO:0006886 intracellular protein transport
GO:0008565 protein transporter activity
GO:0015030 Cajal body
GO:0016071 mRNA metabolic process
GO:0019058 viral infectious cycle
GO:0046796 viral genome transport in host cell
GO:0051028 mRNA transport
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories.
Regulatory
For research purposes only

Applications of EXPORTIN-1 antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Secondary Antibodies Available

Description Product Code Applications Pack Size List Price Quantity
Goat anti Mouse IgG (H/L):HRP STAR207P WB 2 ml

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