EXPORTIN-1 antibody | KL01/4H7

Mouse anti EXPORTIN-1

Product Type
PrecisionAb Monoclonal
Clone
KL01/4H7
Isotype
IgG2b
Format
Purified
Specificity
EXPORTIN-1

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VMA00085
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F IF IP WB 100 µl loader
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Mouse anti Human exportin-1 antibody recognizes exportin-1, also known as Exp1, XPO1 and chromosome region maintenance 1 protein homolog.

Exportin-1 mediates leucine-rich nuclear export signal (NES)-dependent protein transport and specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1 (provided by RefSeq, Jul 2008).

Mouse anti Human exportin-1 antibody detects a band of 112 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
PrecisionAb Antibodies

Target Species
Human
Western Blotting
Anti exportin-1 detects a band of approximately 112 kDa in Jurkat cell lysates.
Product Form
Purified IgG - liquid
Preparation
Mouse monoclonal antibody purified by affinity chromatography on Protein G from tissue culture supernatant
Buffer Solution
Phosphate buffered saline.
Preservative Stabilisers
0.09% Sodium Azide (NaN3).
Immunogen
E. Coli derived recombinant protein, aa 932-1071 of human exportin-1
Approx. Protein Concentrations
IgG concentration 0.5 mg/ml.
Regulatory
For research purposes only.
Guarantee
12 months from date of despatch.
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories.

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Flow Cytometry
Immunofluorescence
Immunoprecipitation
Western Blotting 1/1000
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

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UniProt
O14980
Entrez Gene
XPO1
GO Terms
GO:0005515 protein binding
GO:0000236 mitotic prometaphase
GO:0000776 kinetochore
GO:0003723 RNA binding
GO:0030529 ribonucleoprotein complex
GO:0005829 cytosol
GO:0005635 nuclear envelope
GO:0005642 annulate lamellae
GO:0005730 nucleolus
GO:0006886 intracellular protein transport
GO:0008565 protein transporter activity
GO:0015030 Cajal body
GO:0016071 mRNA metabolic process
GO:0019058 viral infectious cycle
GO:0046796 viral genome transport in host cell
GO:0051028 mRNA transport
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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