ERAB antibody | OTI5E2

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Mouse anti ERAB

Product Type
PrecisionAb Monoclonal
Product Code Applications Pack Size List Price Quantity
100 µl loader

Mouse anti Human ERAB antibody recognizes ERAB, also known as 3-hydroxyacyl-CoA dehydrogenase type-2, HSD17B10, 3-hydroxy-2-methylbutyryl-CoA dehydrogenase, AB-binding alcohol dehydrogenase, amyloid-beta peptide binding alcohol dehydrogenase, short chain dehydrogenase/reductase family 5C, member 1 and short chain type dehydrogenase/reductase XH98G2.

Encoded by the ERAB / HSD17B10 gene, 3-hydroxyacyl-CoA dehydrogenase type-2 is a member of the short-chain dehydrogenase/reductase superfamily. 3-hydroxyacyl-CoA dehydrogenase type-2 is mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids, alcohols, and steroids and has been implicated in the development of Alzheimer's disease. Mutations in the gene are the cause of 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency (MHBD). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined (provided by RefSeq, Jul 2008).

Mouse anti Human ERAB antibody detects a band of 27 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.

Product Details

Target Species
Western Blotting
Anti ERAB detects a band of approximately 27 kDa in HeLa cell lysates
Product Form
Purified IgG - liquid
Mouse monoclonal antibody purified by affinity chromatography from ascites
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
1% Bovine Serum Albumin
50% Glycerol
Full length recombinant human ERAB (HSD17B10) (NP_004484) produced in HEK293T cells

Storage Information

Store undiluted at -20oC, avoiding repeated freeze thaw cycles.
12 months from date of despatch

More Information

Entrez Gene
GO Terms
GO:0005886 plasma membrane
GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity
GO:0005759 mitochondrial matrix
GO:0055114 oxidation-reduction process
GO:0006629 lipid metabolic process
GO:0008033 tRNA processing
GO:0008709 cholate 7-alpha-dehydrogenase activity
GO:0009083 branched chain family amino acid catabolic process
GO:0047015 3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity
PrecisionAb is a trademark of Bio-Rad Laboratories.
For research purposes only

Applications of ERAB antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Secondary Antibodies Available

Description Product Code Applications Pack Size List Price Quantity
Goat anti Mouse IgG (H/L):HRP STAR207P WB 2 ml

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