EGF R (pTyr1173) antibody


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WB ResetMouse anti EGF Receptor (pTyr1173)
- Product Type
- PrecisionAb Monoclonal
- Isotype
- IgG1
- Format
- Purified
- Specificity
- EGF R (pTyr1173)
Mouse anti EGF receptor antibody recognizes the epidermal growth factor receptor, also known as proto-oncogene c-ErbB-1 or receptor tyrosine-protein kinase erbB-1, when phosphorylated at threonine 1173. EGF R plays a role in numerous cellular processes such as cell proliferation and apoptosis through the activation of downstream signaling pathways (Scaltriti and Baselga 2006). EGF R is autophosphorylated at tyrosine 1173 upon ligand binding (Downward et al. 1985). PRMT5- mediated EGF R arginine 1175 methylation modulates EGF R autophoshorylation on tyrosine 1173 (Hsu et al. 2011). EGF R phosphorylation on tyrosine 1173 correlates with a poor prognosis in oral squamous cell carcinomas (OSCC) (Monteiro et al. 2014). |
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- Target Species
- Human
- Western Blotting
- Mouse anti EGF receptor (pTyr1173) detects a band of approximately 175 kDa in A431 pervanadate-treated A431 (treated lysate) cell lysates
- Product Form
- Purified IgG - Liquid
- Preparation
- Mouse monoclonal antibody purified by thiophillic adsorption and size exclusion chromatography from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide
PEG & Sucrose - Immunogen
- Phosphopeptide conjugate to KLH
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories.
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
Western Blotting | ![]() |
1/1000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
---|---|---|---|---|---|---|---|
Goat anti Mouse IgG (H/L):HRP | STAR207P | WB | 2 ml |
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List Price | Your Price | ||||||
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Description | Goat anti Mouse IgG (H/L):HRP |
VMA00752

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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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