EGF R (pSer1047) antibody

Mouse anti EGF Receptor (pSer1047)

Product Type
PrecisionAb Monoclonal
Isotype
IgG1
Format
Purified
Specificity
EGF R (pSer1047)

Product Code Applications Pack Size List Price Your Price Qty
VMA00746
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
WB 100 µl loader
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Mouse anti EGF receptor antibody recognizes the epidermal growth factor receptor, also known as proto-oncogene c-ErbB-1 or receptor tyrosine-protein kinase erbB-1, when phosphorylated at serine 1047. EGF R is a cell surface receptor for members of the epidermal growth factor family. EGF R plays a role in numerous cellular processes such as cell proliferation and apoptosis through the activation of downstream signaling pathways (Scaltriti and Baselga 2006). Serine 1047 is phosphorylated by calmodulin-dependent protein kinase II (CaM kinase II) (Feinmesser et al. 1999). The phosphorylation of serine 1047 is important for EGF receptor desensitization (Countaway et al. 1992). PrecisionAb Antibodies

Target Species
Human
Western Blotting
Mouse anti EGF receptor (pSer1047) detects a band of approximately 175 kDa in pervanadate-treated A431 (treated lysate) cell lysates
Product Form
Purified IgG - Liquid
Preparation
Mouse monoclonal antibody purified by thiophillic adsorption and size exclusion chromatography from tissue culture supernatant
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide
PEG & Sucrose
Immunogen
Phosphopeptide conjugated to KLH
Regulatory
For research purposes only
Guarantee
12 months from date of despatch
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories.

Store undiluted at -20°C, avoiding repeated freeze thaw cycles

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

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Synonyms
Erbb
ERBB1
HER1
UniProt
P00533
Entrez Gene
EGFR
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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