EGF R antibody | IJ01-1A12

Mouse anti EGF Receptor

Product Type
PrecisionAb Monoclonal
Clone
IJ01-1A12
Isotype
IgG1
Format
Purified
Specificity
EGF R

Product Code Applications Pack Size List Price Your Price Qty
VMA00982
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
WB 100 µl loader
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Mouse anti Human EGF receptor antibody recognizes the epidermal growth factor receptor, also known as Proto-oncogene c-ErbB-1 or receptor tyrosine-protein kinase erbB-1.

The protein encoded by EGF R is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGF receptor is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in EGF R are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for EGF R (provided by RefSeq, Jul 2010).
PrecisionAb Antibodies

Target Species
Human
Western Blotting
Mouse anti EGF R antibody detects bands of approximately 177 kDa in A431 cells
Product Form
Purified IgG - liquid
Preparation
Mouse monoclonal antibody purified by affinity chromatography on Protein G from tissue culture supernatant
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
Immunogen
Peptide, aa 1001-1024 (LMDEEDMDDVVDADEYLIPQQGFF) of human EGF R
Approx. Protein Concentrations
IgG concentration 1.0 mg/ml
Regulatory
For research purposes only
Guarantee
12 months from date of despatch
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories

Store undiluted at -20oC, avoiding repeated freeze thaw cycles

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/10000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

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Description Goat anti Mouse IgG (H/L):HRP

UniProt
P00533
Entrez Gene
EGFR
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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