EGF R antibody | G02-2D5
Overexpression of the EGF receptor promotes gene amplification and mutation consequence in cell proliferation, survival, invasion, metastasis, and tumor induced neoangiogenesis (Ciardiello & Tortora, 2008).
Product Details
- Target Species
- Human
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein G from ascites
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Immunogen
- E. coli derived recombinant protein corresponding to aa 363-499 of the human EGF receptor
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Fusion Partners
- Spleen cells from immunised BALB/c mice were fused with cells of the mouse SP2/0 myeloma cell line.
Storage Information
- Storage
- Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. - Guarantee
- 12 months from date of despatch
More Information
Applications of EGF R antibody
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
ELISA | |||
Western Blotting | 1/1000 |
Secondary Antibodies Available
Product Specific References
Further Reading
-
Ciardiello, F. & Tortora, G. (2008) EGFR antagonists in cancer treatment.
N Engl J Med. 358 (11): 1160-74. -
Prenzel, N. et al. (2001) The epidermal growth factor receptor family as a central element for cellular signal transduction and diversification.
Endocr Relat Cancer. 8 (1): 11-31.
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