Cytokeratin 19 antibody
Mouse anti Human cytokeratin 19 antibody recognizes the rod domain (aa 312-335) of human cytokeratin 19 also known as keratin 19 and encoded by the KRT19 gene. Cytokeratin 19 is a 400 amino acid intermediate filament protein lacking a C-terminal tail domain, in contrast to all other intermediate filament proteins.
Cytokeratin expression is observed in striated muscle where it is involved in forming the association between the contractile apparatus and dystrophin (Stone et al. 2005). Expression is also seen in many ductal and glandular cells together with a restricted set of normal and neoplastic epithelial cells.
Mouse anti Human cytokeratin 19 antibody detects a band of ~44kDa in Western blotting using multiple human cell-line lysates.
Cytokeratin expression is observed in striated muscle where it is involved in forming the association between the contractile apparatus and dystrophin (Stone et al. 2005). Expression is also seen in many ductal and glandular cells together with a restricted set of normal and neoplastic epithelial cells.
Mouse anti Human cytokeratin 19 antibody detects a band of ~44kDa in Western blotting using multiple human cell-line lysates.
Product Details
- Target Species
- Human
- Western Blotting
- Anti Cytokeratin 19 antibody detects a band of approximately 44 kDa in MCF7 cell lysates.
- Product Form
- Purified IgG - liquid
- Preparation
- Mouse monoclonal antibody purified by affinity chromatography on Protein G from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Immunogen
- Human breast cancer cell line MCF7
Storage Information
- Storage
- Store undiluted at -20oC, avoiding repeated freeze thaw cycles.
- Guarantee
- 12 months from date of despatch
More Information
- UniProt
- P08727
- Entrez Gene
- KRT19
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories.
- Regulatory
- For research purposes only
Applications of Cytokeratin 19 antibody
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting | 1/1000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
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