Mouse anti Human Cytokeratin 18 antibody, clone CY90 recognizes human cytokeratin 18, a 45 kDa member of the acidic family of Cytokeratins. Cytokeratin 18 is often expressed in combination with cytokeratin 8. This antibody stains a range of simple epithelial, but not stratified squamous epithelia.
- Target Species
- Product Form
- Ready To Use
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
|0.5%||Bovine Serum Albumin|
- Human A-431 and MCF-7 cell lines
- Store at +4oC.
DO NOT FREEZE.
This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.
- 18 months from date of despatch.
- Entrez Gene
- GO Terms
structural molecule activity
anatomical structure morphogenesis
Golgi to plasma membrane CFTR protein transport
negative regulation of apoptosis
interspecies interaction between organisms
perinuclear region of cytoplasm
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of Cytokeratin 18 antibody
|Immunohistology - Frozen
|Immunohistology - Paraffin 1
- 1This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. Serotec target unmasking fluid (STUF) product code BUF025A is recommended for this purpose.
Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
- Histology Positive Control Tissue
Copyright © 2019 Bio-Rad Antibodies (formerly AbD Serotec)
Secondary Antibodies Available
Useful Reagents Available
Application Based External Images
Immunohistology - Paraffin
Product Specific References
References for Cytokeratin 18 antibody
MacFarlane, M. et al. (2000) Active caspases and cleaved cytokeratins are sequestered into cytoplasmic inclusions in TRAIL-induced apoptosis.
J Cell Biol. 148 (6): 1239-54.
Holliday, D. et al. (2009) Novel multicellular organotypic models of normal and malignant breast: tools for dissecting the role of the microenvironment in breast cancer progression.
Breast Cancer Res 11: R3
Clark, S.E. et al. (2011) Molecular subtyping of DCIS: heterogeneity of breast cancer reflected in pre-invasive disease.
Br J Cancer. 2011 Jan 4;104(1):120-7
Ginzberg, H.H. et al (2001) Neutrophil-mediated epithelial injury during transmigration: role of elastase.
Am J Physiol Gastrointest Liver Physiol. 281: G705-17.