CTBP2 antibody | CD02/2B4

100% Secure


Mouse anti CTBP2

Product Type
PrecisionAb Monoclonal
Clone
CD02/2B4
Isotype
IgG2a
Format
Purified
Product Code Applications Pack Size List Price Quantity
VMA00896
Datasheet
WB
SDS
100 µl loader

Mouse anti CTBP2 antibody recognizes c-terminal-binding protein 2.

CTBP2 is a transcriptional corepressor and modulator of a range of cellular processes. This protein is able to induce the epithelial to mesenchymal transition (EMT), and can bind to beta catenin and regulate Wnt signaling. CTBP2 is also able to affect cell migration by at least two mechanisms (Paliwal et al. 2012). CTBP2 can inhibit tumor suppressor activity and apoptosis, and is overexpressed in a variety of cancers including prostate cancer, hepatocellular carcinoma, and ovarian cancer (Dai et al. 2017). CTBP2 has been suggested as a potential biomarker for tumorigenesis, and could be a prognostic indicator of prostate cancer (Zhang et al. 2015).

Product Details

Target Species
Human
Western Blotting
Mouse anti CTBP2 antibody detects a band of approximately 47 kDa in HEK293 cell lysates
Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse
Rat
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - Liquid
Preparation
Mouse monoclonal antibody affinity purified on Protein G from tissue culture supernatant
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide
Immunogen
E. coli-derived recombinant protein of amino acids 1-445 of human CTBP2
Approx. Protein Concentrations
IgG concentration 1.0 mg/ml
Fusion Partners
Spleen cells from immunised BALB/c mice were fused with cells of the mouse SP2/0 myeloma cell line

Storage Information

Storage
Store undiluted at -20°C, avoiding repeated freeze thaw cycles
Guarantee
12 months from date of despatch

More Information

UniProt
P56545
Entrez Gene
CTBP2
GO Terms
GO:0005515 protein binding
GO:0055114 oxidation-reduction process
GO:0006350 transcription
GO:0019079 viral genome replication
GO:0008285 negative regulation of cell proliferation
GO:0016564 transcription repressor activity
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0017053 transcriptional repressor complex
GO:0030054 cell junction
GO:0045202 synapse
GO:0050872 white fat cell differentiation
GO:0051287 NAD binding
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories
Regulatory
For research purposes only

Applications of CTBP2 antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Secondary Antibodies Available

Description Product Code Applications Pack Size List Price Quantity
Goat anti Mouse IgG (H/L):HRP STAR207P WB 2 ml

Fluorescent Spectraviewer

Watch the Tool Tutorial Video ▸

How to Use the Spectraviewer

Watch the Tool Tutorial Video ▸
  • Start by selecting the application you are interested in, with the option to select an instrument from the drop down menu or create a customized instrument
  • Select the fluorophores or fluorescent proteins you want to include in your panel to check compatibility
  • Select the lasers and filters you wish to include
  • Select combined or multi-laser view to visualize the spectra